LMNA

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LMNA

A gene on chromosome 1q22 that encodes lamin A/C, a protein highly conserved in evolution that forms part of the two-dimensional matrix of proteins located next to the inner nuclear membrane. Lamins are involved in providing nuclear stability and chromatin structure, and in gene expression.

Molecular pathology
LMNA mutations cause the so-called laminopathies—e.g., Charcot-Marie-Tooth disease type 2B1, progeria (Hutchinson-Gilford syndrome), dilated cardiomyopathy, Emery-Dreifuss muscular dystrophy type 2, familial partial lipodystrophy, limb-girdle muscular dystrophy type 1B, mandibuloacral dysplasia, and some cases of Werner syndrome.

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References in periodicals archive ?

LDP2 replaces the first London Development Panel (LDP1) which expired in 2017.

Transport for London unveils more plans for 450 new homes on car parks at Harrow Tube stations; The local community will be asked to give their opinions on the development

Out of them, there were two couples of hybrid genotypes originated from the same parents, of which one couple is PH8 and PH9 and the other one is LDP1 and LDP2.

1A), VN1, VN3 and Keoamtich were presented in one small sub-group forming a group of small- leaved China type, and the remaining small sub-group was nested by the crosses LDP1 and LDP2 (Assam-small leaved China type, and also known as offspring of the same parents), and PH10 (small leaved China type).

Among them, only Keoamtich was appeared alone, while the same parental crosses LDP1 and LDP2 were presented in one sub-group, and the single cluster consisted of DS13 and DS15 together with VN1 were presented in the other sub-group.

Diversity of Tea (Camellia sinensis) Grown in Vietnam based on Morphological Characteristics and Inter-primer Binding Sites (iPBS) Marker

The report added: "Since LDP1 was withdrawn in March, work on preparing LDP2 has commenced.

Housing blueprint rethink ordered

Table 1 Partisan Swings in Japanese Elections 1 2 3 4 LDP (-1993) JSP (-1993) LDP (2000-) DPJ (2000-) Last margin 14.54 10.73 13.14 15.26 (1.50) ** (1.91) ** (2.219) ** (3.111) ** Party swing 27.05 27.72 33.66 23.95 (4.80) ** (3.00) ** (3.373) ** (3.489) ** Urban -0.13 0.12 -1.72 -1.99 (-0.05) * (0.06) * (0.442) ** (0.990) * Constant 1.49 0.75 0.96 1.14 (0.15) ** (0.19) ** (0.384) * (-0.84) Proportional -0.6% +1.2% +57.9% +40.5% reduction in errors Pseudo-[R.sup.2] 0.06 0.07 0.46 0.33 N 3,308 1,431 631 253 Descriptive Statistics (Median) LDP1 JSP LDP2 DPJ Last margin 0.041 0.035 0.149 0.071 Party swing -0.004 -0.007 0.014 0.030 Urban (a) 2 3 0.510 0.860 Notes: Dependent variable = Win versus Loss (1, 0) for incumbent candidates.

The nationalization of Japanese elections

New clonal types, such as LDP1, LDP2, PH1 and #777 are slowly being introduced by the Northern Mountainous Agriculture and Forestry Science Institute (formerly, Phu Ho Tea Research Institute) for higher yields, higher quality or improved adaptation to poor soil quality.