LDL

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LDL

 
low-density lipoprotein.

LDL

Abbreviation for low density lipoprotein. see under lipoprotein.

LDL

(ĕl′dē′ĕl′)
n.
A lipoprotein with a relatively high concentration of lipids and low concentration of protein that incorporates cholesterol and transports it to cells. High levels are associated with an increased risk of atherosclerosis and coronary artery disease. Also called LDL cholesterol.

LDL

Low-density lipoprotein Beta-lipoprotein A 3000 kD plasma lipoprotein–
normal serum concentration 60-155 mg/dL–which has a central role in transporting cholesterol from the intestine to the liver ↑ in Nephrotic syndrome, obstructive jaundice, uncontrolled DM, type II hypercholesterolemia; ↓ in Familial LDL deficiency. See Cholesterol, Small LDL. Cf HDL.

LDL

Abbreviation for malondialdehyde-modified low-density lipoprotein.

LDL

Abbrev. for low density LIPOPROTEINS.

Low density lipoproteins (LDL)

A blood-plasma lipoprotein that is high in cholesterol and low in protein content and that carries cholesterol to cells and tissue; also called bad cholesterol.

Patient discussion about LDL

Q. How can I increase my HDL cholesterol levels? My Doctor told me that my cholesterol levels are not good and that I should lower my LDL and higher my HDL. I understand how to lower the cholesterol, but how can I increase the HDL?

A. a good way is to eat boiled fish, and instead of regular oil, add olive oil to your salad.

Q. Improving High Triglycerides I take Tricor for high triglyceride levels; I have a healthy level of total cholesterol, with low LDL, very good HDL. I am now being treated for hypothyroidism, but my doctor says that it's also genetic (I had almost the exact same level number as my brother). How can I work to get my triglycerides under control?

A. High level of triglycerides are generally both genetic and diet related. If you are consuming a high fat containing diet then your level of triglycerides will be increased. On the other hand, regardless of your good cholesterol levels, if you start lowering the amount of fat in your food (less oil, less sweets, less red meat) and combine it with physical activity you can lower your triglycerides level, especially if you are already on medications.

Q. Does wight loss lowers cholesterol? I'm 5'5, 175 lbs, 40 years-old man. After my doctor found that I have high LDL cholesterol, I was advised to try to lower my weight in order to reduce my cholesterol levels. Otherwise I'll have to start taking medications. Can it really do something? As far as I know, cholesterol level are pretty much a genetic thing, and one can be very thin but still have high cholesterol levels.

A. One of the best things you should do is to take a good multivitamin multimineral supplement. And of course, changing your lifestyle. Supplementing your diet with vitamins can help you reduce your LDL cholesterol levels and increase HDL. Also, increase your intake of omega 3 fatty acids, but make sure that you know the source they are from before taking them.

More discussions about LDL
References in periodicals archive ?
Brown, "The LDL receptor," Arteriosclerosis, Thrombosis, and Vascular Biology, vol.
Mutations may result either in complete absence of the LDL receptor, defective binding of LDL to the receptor or defective internalisation and transport of the LDL.
Familial hypercholesterolemia, or FH, an autosomal dominant disorder of lipoprotein disorder with a prevalence of about 1 in 500, results from mutations of the LDL receptor gene [1].
(16) Polyunsaturated FAs have been shown to reduce plasma levels of LDL and VLDL, possibly due to increased uptake into cells and increased expression of LDL receptors in the liver.
The scientists also found that polyphenols appear to increase the activity of LDL receptors, proteins that help lower "bad" cholesterol levels.
Recent data suggest that soy protein subunits, particularly 7S, directly activiate LDL receptors in the human liver, thus providing a novel mechanism of plasma cholesterol reduction different from currently available diets and hypolipidemic drugs.
In concert with HMGCoAR, LDL receptors (LDLRs) are upregulated to import cholesterol by binding apoB-containing lipoproteins.
At the same time, expression of the gene, which produces LDL receptors that help to clear plasma cholesterol was increased by 60%.
Cardiologist David Wald, of the University of London, said: "It has the potential to prevent a major cause of coronary heart disease." One in 500 people have familial hypercholesterolaemia which means they have few LDL receptors that remove cholesterol.
Additionally, a large apoB-100 molecule is located at one pole of the LDL and acts as a recognition site for LDL receptors on almost all cells of the body (Pentikainen et al., 2000).