LDL cholesterol


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Related to LDL cholesterol: Triglycerides, HDL cholesterol
Cholesterol transported in the circulation by low-density lipoprotein, the elevation of which is directly related to the risk of coronary artery disease and cholesterol-related morbidity

LDL cholesterol

Bad cholesterol Cholesterol carried by LDL which, when elevated, is a major risk factor for ASHD. See HDL/LDL ratio. Cf HDL-cholesterol.

LDL Cholesterol

Low-density lipoprotein cholesterol is the primary cholesterol molecule. High levels of LDL increase the risk of coronary heart disease. LDL is nicknamed "bad" cholesterol.

Patient discussion about LDL cholesterol

Q. Does wight loss lowers cholesterol? I'm 5'5, 175 lbs, 40 years-old man. After my doctor found that I have high LDL cholesterol, I was advised to try to lower my weight in order to reduce my cholesterol levels. Otherwise I'll have to start taking medications. Can it really do something? As far as I know, cholesterol level are pretty much a genetic thing, and one can be very thin but still have high cholesterol levels.

A. One of the best things you should do is to take a good multivitamin multimineral supplement. And of course, changing your lifestyle. Supplementing your diet with vitamins can help you reduce your LDL cholesterol levels and increase HDL. Also, increase your intake of omega 3 fatty acids, but make sure that you know the source they are from before taking them.

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References in periodicals archive ?
The Phase 3 trial was designed to assess the effect of evinacumab on LDL cholesterol and other lipid-related endpoints.
After a median follow-up of 26 months, the incidence of the study's primary endpoint (cardiovascular death, MI stroke, hospitalization for unstable angina, or coronary revascularization) dropped by a statistically significant 15% in patients with an achieved LDL cholesterol of 20-49 mg/dl, compared with patients whose four weeks LDL cholesterol was at or above 100mg/dl (primarily patients randomized to the study's control arm), by 24% in all patients with LDL cholesterol less than 20 mg/dl and by 31% in the 2% of patients whose LDL cholesterol levels fell below 10 mg/dl.
In order to prevent LDL cholesterol from reaching high levels in the blood, specialists advise people to adhere to diets that promote high HDL and low LDL cholesterol.
The TNT trial randomized more than 10,000 subjects with known coronary artery disease and a baseline LDL cholesterol level below 130 mg/dL to receive either 10 or 80 mg/day of atorvastatin, with fasting lipids measured in a central laboratory at 3 and 12 months, then annually.
Among 25,982 FOURIER patients with a measured LDL cholesterol level after 4 weeks on treatment and no study event as of then, 31% had their LDL cholesterol cut to 20-49 mg/dL, 8% achieved a LDL cholesterol level of 10-19 mg/dL, and 2% reached a remarkable LDL cholesterol level of below 10 mg/dL, as low as herbivores such as rabbits and deer.
The researchers then examined the association between female sex and achieving an LDL cholesterol level of less than 70 mg/dl in patients at very high risk of a cardiovascular event.
With both types of therapies, every 1 millimole per liter (39 milligrams per deciliter) reduction in LDL cholesterol represented a 23 percent decrease in the risk of major cardiovascular events, the team reports.
In this study, we tested the hypothesis that extreme concentrations of nonfasting remnant and LDL cholesterol are equal contributors to risk of IHD, MI, and all-cause mortality.
Statin drugs, which include rosuvastatin (Crestor), atorvastatin (Lipitor), and simvastatin (Zocor), are commonly prescribed for patients who have already had a cardiovascular event, such as a heart attack or stroke, and they also are given to patients who are at high risk of these events due to elevated LDL cholesterol levels.
Research shows that people with HIV infection have a twice higher heart attack rate than people without HIV.(2) Researchers who conducted this new study of hypertension and LDL cholesterol (sometimes called "bad cholesterol") suggested three reasons why people with HIV have a higher cardiovascular disease rate than people without HIV: