LDL


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LDL

 
low-density lipoprotein.

LDL

Abbreviation for low density lipoprotein. see under lipoprotein.

LDL

(ĕl′dē′ĕl′)
n.
A lipoprotein with a relatively high concentration of lipids and low concentration of protein that incorporates cholesterol and transports it to cells. High levels are associated with an increased risk of atherosclerosis and coronary artery disease. Also called LDL cholesterol.

LDL

Low-density lipoprotein Beta-lipoprotein A 3000 kD plasma lipoprotein–
normal serum concentration 60-155 mg/dL–which has a central role in transporting cholesterol from the intestine to the liver ↑ in Nephrotic syndrome, obstructive jaundice, uncontrolled DM, type II hypercholesterolemia; ↓ in Familial LDL deficiency. See Cholesterol, Small LDL. Cf HDL.

LDL

Abbreviation for malondialdehyde-modified low-density lipoprotein.

LDL

Abbrev. for low density LIPOPROTEINS.

Low density lipoproteins (LDL)

A blood-plasma lipoprotein that is high in cholesterol and low in protein content and that carries cholesterol to cells and tissue; also called bad cholesterol.

Patient discussion about LDL

Q. How can I increase my HDL cholesterol levels? My Doctor told me that my cholesterol levels are not good and that I should lower my LDL and higher my HDL. I understand how to lower the cholesterol, but how can I increase the HDL?

A. a good way is to eat boiled fish, and instead of regular oil, add olive oil to your salad.

Q. Improving High Triglycerides I take Tricor for high triglyceride levels; I have a healthy level of total cholesterol, with low LDL, very good HDL. I am now being treated for hypothyroidism, but my doctor says that it's also genetic (I had almost the exact same level number as my brother). How can I work to get my triglycerides under control?

A. High level of triglycerides are generally both genetic and diet related. If you are consuming a high fat containing diet then your level of triglycerides will be increased. On the other hand, regardless of your good cholesterol levels, if you start lowering the amount of fat in your food (less oil, less sweets, less red meat) and combine it with physical activity you can lower your triglycerides level, especially if you are already on medications.

Q. Does wight loss lowers cholesterol? I'm 5'5, 175 lbs, 40 years-old man. After my doctor found that I have high LDL cholesterol, I was advised to try to lower my weight in order to reduce my cholesterol levels. Otherwise I'll have to start taking medications. Can it really do something? As far as I know, cholesterol level are pretty much a genetic thing, and one can be very thin but still have high cholesterol levels.

A. One of the best things you should do is to take a good multivitamin multimineral supplement. And of course, changing your lifestyle. Supplementing your diet with vitamins can help you reduce your LDL cholesterol levels and increase HDL. Also, increase your intake of omega 3 fatty acids, but make sure that you know the source they are from before taking them.

More discussions about LDL
References in periodicals archive ?
To gain further insight into associations between LDL subclasses and AIS, we evaluated LDL subclasses according to AIS subtypes.
We saw benefits that continues down to the lowest LDL levels, so it's hard to pick a LDL target.
Hazen says he and his preventive cardiology colleagues routinely aim for a minimal LDL goal of less than 70 mg/ dl in secondaryprevention patients (i.e., those with cardiovascular disease).
This medication prevents the absorption of bile acid in the small intestine, lowers LDL, increases HDL slightly, and, to a little extent, lowers triglycerides.
While FOURIER's event curve continued to drop as LDL cholesterol fell below 10 mg/dL, the study's wide-ranging safety assessment showed no signal of harm at the lowest levels.
Nuclear magnetic resonance (NMR) can be employed for studying of lipoprotein classes in blood plasma, including subclasses of LDL. However, the results of particle size measurement by NMR differ significantly from the GGE data in the same patients and can not be directly compared.
However, the data in the present meta-regression analysis raise the possibility that other interventions, especially those that ultimately act predominantly through upregulation of LDL receptor expression, may provide additional options and may potentially be associated with the same relative clinical benefit per each 1 millimole per liter reduction in LDL-C."
Patients with early-onset peripheral vascular disease have increased levels of autoantibodies against oxidized LDL. Arterioscler Thromb Vasc Biol 1995 Apr;15(4):441-445.
Calculated low density lipoprotein cholesterol levels frequently underestimate directly measured low density lipoprotein cholesterol determinations in patients with serum triglyceride levels < or =4.52 mmol/l: an analysis comparing the LipiDirect magnetic LDL assay with the Friedewald calculation.
As a consequence of decreased de novo cholesterol synthesis caused by statins, LDL receptors are up-regulated resulting in increased clearance of circulating LDL particles.
Finally, if your LDL remains high after a two-month attempt at lowering it with diet and exercise, return to your doctor and get your prescription for a statin: It is crucial to reduce your LDL now so you can protect yourself in the future, especially from cardiovascular events including stroke and heart attack.