LD50


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Related to LD50: LC50

LD50

median lethal dose.

LD50

symbol for median lethal dose.

median lethal dose

The average amount of a drug, toxin, chemical substance/mixture or microorganism capable of killing 1/2 of the test animals exposed under specific test conditions. Median lethal dose (LD50) is commonly expressed in mg/kg, by oral intake or skin exposure.

LD50

Lethal dose50, median lethal dose The radiation dose that is lethal to 50% of those exposed–2.5-6.0 Gy, assuming that optimal care—ie transfusions, trauma and nursing care, antibiotics and nutrition—is available

LD50

In pharmacology, a dose that proves lethal to 50% of a given population.

LD50

The dose of a poison that kills half the subjects exposed to it. Used as a measure of the toxicity of drugs and other substances.

LD50

see LETHAL DOSE.

LD50

Dosage of drug or numbers of microorganisms or other pathogens that kills 50% of a test population.

LD50,

LD50

median lethal dose; the dose that will kill 50% of the tested group.
References in periodicals archive ?
Effects of LD50 dose of Black Pakistani Cobra venom on Erythrogram in envenomated mice.
Animals: 30 male CF1 mouse (10-12 weeks old) were intraperitoneally (ip) injected with 1/12 of the LD50 (240 mg/Kg body weight) of commercial Malathion (95,2% w/v); Anasac, Santiago, Chile [CAS 16.
The data were analyzed with a Finney computer program to determine the LD50 values.
LD50 and LT50 values were calculated using log-probit regression analysis.
LD50 (the concentration/dose that kills 50 % of the treated animals) was 1397 mg/kg with 95 % confidence limit (1139 mg/kg 1714 mg/kg) calculated with trimmed spearman-karber (TSK) software.
rohita exhibited significantly higher mean Cd LD50 values of 144.