ACADL

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ACADL

A gene on chromosome 2q34-q35 that encodes an acyl-CoA dehydrogenase which is a mitochondrial flavoenzyme involved in fatty acid and branched chain amino-acid metabolism. It is one of four enzymes that catalyse the first step of mitochondrial beta-oxidation of straight-chain fatty acid.

Molecular pathology
Defects of ACADL cause long-chain acyl-CoA dehydrogenase (LCAD) deficiency, leading to nonketotic hypoglycaemia.
References in periodicals archive ?
LCAD instructor Derek Sunshine is currently teaching the curriculum.
LCAD provides a small detector incorporating the latest technology to discrete groups of personnel, such as a fire team, operating outside the coverage of MCAD.
The UK requirement is for many thousands, with LCAD an essential part of the suite of NBC Defence equipment available to UK armed forces.
MCAD and LCAD form a very strong two-tier detection system and maintain our proud record of equipping UK troops with the most advanced battlefield identification and alarm capability.
MCAD and LCAD use a technology called Ionic Mobility Spectrometry to detect and identify chemical warfare agents and TICS, at levels at which these substances begin to cause harmful effects to troops operating in their presence.
Another advantage of LCADS is that it comes prepacked from the manufacturer, saving countless man-hours of rigging work and speeding up the process.
By the establishment and funding of the LCADS program, it initiated the development and fielding of low-cost airdrop capabilities.
The most important requirement of the 2002 operational requirements document was for LCADS components to reduce costs by 55 percent (threshold) to 80 percent or more (objective) over current CDS components.
At once, the LCADS team's attention turned to the light, easy-to-rig container developed by the Natick team at the time of the operation in Bosnia.
As the Natick low-cost container was further along in the development process than industry's concept, the in-house approach to the LCADS container solution began.
The LCC is the first of three LCADS components to be developed.