LAIV


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LAIV

live attenuated influenza vaccine.
See: vaccine
References in periodicals archive ?
LAIV represents about 8% of the 171176 million doses that were projected to be available during the 2016-2017 season; however, it represents nearly one-third of doses given to children.
Whether the recommendation against LAIV will continue after this season is also unknown.
For children and adults with chronic medical conditions conferring a higher risk for influenza complications, data on the relative safety and efficacy of LAIV and IIV are limited.
This was a prospective observational cohort study comparing nasal responses (virus quantity, host defense factors) to standard doses of LAIV in individuals with varying exposures to tobacco smoke.
By using base case assumptions, results for LAIV are slightly more favorable than IIV (compared to no vaccination), and vaccination with LAIV is the preferred strategy.
Vivaldi plans to file an Investigational New Drug application and begin clinical trials of its lead LAIV in 2010.
But LAIV data in other age groups were less impressive.
The document will also include information about dosing and administration of LAIV as well as storage, which could prove troublesome for some practices.
In the immediate past season, the predominant influenza strain circulating was H1N1 pdm09, against which the LAIV appeared to be minimally, if at all, effective.
The influenza vaccine footnote was updated to reflect revised contraindications for LAIV: LAIV should not be administered to some persons, including 1) persons who have experienced severe allergic reactions to LAIV, any of its components, or to a previous dose of any other influenza vaccine; 2) children aged 2 through 17 years receiving aspirin or aspirin-containing products; 3) persons who are allergic to eggs; 4) pregnant women; 5) immunosuppressed persons; 6) children aged 2 through 4 years with asthma or who had wheezing in the past 12 months; and 7) persons who have taken influenza antiviral medications in the previous 48 hours.
LAIV is recommended preferentially for various age groups in the United Kingdom, Canada, Israel, and Germany, as well as in Oregon and Washington.