L-forms

L-forms

[named for Lister Institute]
Spontaneous variants of bacteria that replicate as filterable spheres with defective or absent cell walls. They are filterable because of their flexibility rather than their size. Stable forms may grow for an indefinite time in a wall-less state. Organisms of the unstable form are capable of regenerating their cell walls and reverting to their antecedent bacterial form. The ability of L-forms to cause disease is unknown.
Synonym: L-phase variants
References in periodicals archive ?
MacDonald describes L-forms as "sort of like soap bubbles that can stretch out and contain various boundaries, and are not as easy to identify as spirochetes.
Armstrong said their method is very selective at separating out the D- and L-forms.
L-forms are very heterogeneous insize and shape and generally require osmotic stabilisers, such as 0.