Bence Jones myeloma

(redirected from L-chain disease)

Bence Jones my·e·lo·ma

(bents jōnz),
multiple myeloma in which the malignant plasma cells excrete only light chains of one type (either κ or λ); lytic bone lesions occur in about 60% of the cases, and light chains (Bence Jones protein) occur in the urine; amyloidosis and severe renal failure are more common than in multiple myeloma.
[Henry Bence Jones]

Bence Jones,

Henry, English physician, 1814-1873.
Bence Jones albumin
Bence Jones cylinders - slightly irregular, relatively smooth, rod-shaped or cylindroid bodies of fairly tenacious, viscid proteinaceous material in the fluid of the seminal vesicles.
Bence Jones myeloma - multiple myeloma in which the malignant plasma cells excrete only light chains of one type (either kappa or lambda). Synonym(s): L-chain disease; L-chain myeloma
Bence Jones proteins - proteins with unusual thermosolubility found in the urine of patients with multiple myeloma, consisting of monoclonal immunoglobulin light chains.
Bence Jones reaction - the classic means of identifying Bence Jones protein.
Bence Jones test