carnosine

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carnosine

[kahr´no-sēn]

a dipeptide composed of beta-alanine and histidine, found in skeletal muscle of vertebrates.

car·no·sine

(kar'nō-sēn),

N-β-alanyl-l-histidine; the dominant nonprotein nitrogenous component of brain tissue, first found in relatively high amounts in muscle; chelates copper and activates myosin ATPase.

Synonym(s): ignotine, inhibitine

[L. carnosus, fleshy, fr. caro, flesh, + -ia]

carnosine

/car·no·sine/ (-sēn) a dipeptide composed of β-alanine and histidine, found in skeletal muscle and the brain in humans; it may be a neurotransmitter.

carnosine

[kär′nōsēn]

Etymology: L, caro,

a dipeptide composed of beta-alanine and histidine, in humans found in skeletal muscle and in the brain, particularly in the primary olfactory pathways. It may play a role as a neurotransmitter.

carnosine

A dipeptide composed of beta-alanine and histidine that is concentrated in skeletal muscle and the brain. While its function is unknown, carnosine has antioxidant properties, counteracts glycation, chelates divalent metal ions and acts as a buffer, stabilising the pH of anaerobically contracting muscle.

carnosine

a dipeptide composed of beta-alanine and histidine, found in skeletal muscle of vertebrates.

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References in periodicals archive ?

Non-enzymatic glycosylation of the dipeptide L-carnosine, a potential anti-protein-cross-linking agent.

Lithium ascorbate as a protector of human blood biomolecules under ethanol impact

L-carnosine reduces telomere damage and shortening rate in cultured normal fibroblasts.

New studies validate age-delaying effects of carnosine

Yamaguchi, "Acceleration of metabolism of stress-related substances by L-carnosine," Journal of the Physiological Society of Japan, vol.

Use of Carnosine for Oxidative Stress Reduction in Different Pathologies

In 2006, Babizhayev reported that the L-carnosine-related peptidomimetic N-acetylcarnosine (N-acetyl-beta-alanyl-L-histidine) can act as a timed-release (carrier) stable version of L-carnosine in cosmetic preparations, including lubricants.

Cosmeceutical critique: carnosine

L-carnosine and ALA are powerful micronutrients with various biological functions and are often used as health supplements (Kim et al.

Effects of dietary L-carnosine and alpha-lipoic acid on growth performance, blood thyroid hormones and lipid profiles in finishing pigs

L-Carnosine is a [beta]-alanyl histidine dipeptide that is endogenously present in appreciable amounts in skeletal muscles, in the lens, and in relatively lower concentrations in other human tissues [22].

On the Anticataractogenic Effects of L-Carnosine: Is It Best Described as an Antioxidant, Metal-Chelating Agent or Glycation Inhibitor?

Applicability of zinc complex of L-carnosine for medical use.

Natural support for stomach health

Fifty patients (mean age, 62 years) with stable heart failure (New York Heart Association class II or III) and a left ventricular ejection fraction (LVEF) of 45% or less on optimal medical therapy were randomly assigned to receive 500 mg per day of L-carnosine or no L-carnosine (control group) for 6 months.

L-carnosine for heart failure

Chemicals for HPLC analysis were obtained as follows: standard L-carnosine (99% purity) solution from Sigma Inc.

Effects of supplementary blood meal on carnosine content in the breast meat and laying performance of old hens

Kinetic, pharmacological and activity-dependent separation of therapeutic targeting: transcorneal penetration and delivery of L-carnosine in the aqueous humor and hormone-like hypothalamic antiaging effects of the instilled ophthalmic drug through a safe eye medication technique," Recent Patents on Drug Delivery and Formulation, vol.

Comment on "Use of Carnosine for Oxidative Stress Reduction in Different Pathologies"

Patient One GastroOne is a Strawberry flavored supplement designed to support gastrointestinal (GI) health and function, combining L-Glutarnine, N-Acetyl-D-Glucosamine (NAG), De-glycyrrhizinated licorice extract (DGL), aloe vera, slippery elm, marshmallow root, fenugreek, mucin, Methylsulfonylrneth--ane (MSM), chamomile, ginger, quercetin, FiberAid and Zinc L-Carnosine.