carnitine

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Related to L-carnitine: taurine, acetyl l-carnitine, L-arginine

carnitine

 [kahr´nĭ-tēn]
a derivative of betaine found in skeletal muscle and liver; it is necessary for the mitochondrial oxidation of fatty acids.

car·ni·tine

(kar'ni-tēn),
A trimethylammonium (betaine) derivative of γ-amino-β-hydroxybutyrate, formed from Nε,Nε,Nε-trimethyllysine and from γ-butyrobetaine; the l-isomer is a thyroid inhibitor found in muscle, liver, and meat extract; l-carnitine is an acyl carrier with respect to the mitochondrial membrane and thus stimulates fatty acid oxidation.
Synonym(s): BT factor, vitamin BT
[L. caro carn-, flesh + ine]

carnitine

(kär′nĭ-tēn′)
n.
A compound that functions in fatty acid metabolism by transporting fatty acids into mitochondria for energy production. It is naturally produced in the body and is present in many animal products, especially red meat. It is also sold as a dietary supplement for its purported health benefits.

carnitine

Chemistry
An essential amino acid that transports long-chain fatty acids across the inner mitochondrial membrane for breakdown to CO2 or ketone bodies; it acts as an acyl (fatty acid carrier). Carnitine is endogenous (synthesised in the liver and kidneys from lysine and methionine) or exogenous (from red meat and dairy products).

Fringe nutrition
Carnitine allegedly enhances athletic performance, prevents heart disease, controls weight and has anti-ageing properties; current data does not support these assertions.

car·ni·tine

(kahr'ni-tēn)
A trimethylammonium (betaine) derivative of gamma-amino-beta-hydroxybutyric acid, formed from NE,NE,NE -trimethyllsine and from gamma-butyrobetaine; the l-isomer is a thyroid inhibitor found in muscle, liver, and meat extracts; l-carnitine is an acyl carrier with respect to the mitochondrial membrane; it thus stimulates fatty acid oxidation.
[G. karnin, an alkali derived from meat]

car·ni·tine

(kahr'ni-tēn)
Compound found in dairy and meat that stimulates fatty acid oxidation.
[G. karnin, an alkali derived from meat]
References in periodicals archive ?
Mean serum ALT (U/L) level of fast growing broiler strains during heat stress fed on alpha-tocopherol, ginger and L-carnitine.
Effect of L-carnitine supplementation on red blood cells deformability in hemodialysis patients.
Usually, the positive results of the supplementation of L-carnitine in aquafeeds are attributed to the protein sparing effect as a result of increased energy from lipid oxidation (Mohseni & Ozorio, 2014).
Effect of L-carnitine, multivitamins and their combination in the treatment of idiopathic male infertility.
Conclusions: Acute L-carnitine supplementation possibly affects exercise performance and triglycerides in athletes rather than sedentarymen.
Li, "Effective dosing of l-carnitine in the secondary prevention of cardiovascular disease: a systematic review and meta-analysis," BMC Cardiovascular Disorders, vol.
Effects of L-carnitine supplementation on muscular symptoms in hemodialyzed patients.
Our study shows that higher levels of TMAO, a metabolite of L-carnitine derived from red meat, is associated with poorer outcomes associated with acute heart failure-one of the main diseases of the heart, Suzuki added.
Although L-carnitine and betaine can be synthesized in humans, the intake of these compounds from food could be advantageous for maintaining or improving health.
Lecithin, choline, betaine, and L-carnitine each feature the same TMA moiety and play a central role in human metabolism.
Impact of vigorous exercise on serum levels of L-carnitine in prisoners in Colombia