l-asparaginase


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Related to l-asparaginase: methotrexate, cyclophosphamide, etoposide, vincristine

l-asparaginase

Oncology A chemotherapeutic used for lymphomas and lymphocytic leukemia Adverse effects Vomiting, hepatic dysfunction, allergic reaction, lethargy
References in periodicals archive ?
The interest for developing and improving Production of L-asparaginase from new sources Increased after a recent shortage of supply in the Brazilian market, which threats the treatment of Hundreds of patients.
L-Asparaginase has received increased attention in recent years for its anticarcinogenic potential and is used as a chemotherapeutic agent for acute lymphocytic leukemia and less frequently for acute myeloblastic leukemia, chronic lymphocytic leukemia, Hodgkin's disease, melonosarcoma and non-Hodgkin's lymphoma [7-11].
5) To our knowledge, lomustine use has not been reported in avian species, and only one case of L-asparaginase being used has been reported, with a survival time of 8 weeks.
The present study reveals that soil is a rich source for the isolation of L-asparaginase producing bacteria.
L-asparaginase was estimated by Nesslerization as described by Imada et al.
Guinea pigs have in their blood an enzyme called L-asparaginase, which destroys the amino acid L-asparagine.
The Madison-Wisconsin protocol, a combination of L-asparaginase, vincristine, prednisone, cyclophosphamide, and doxorubicin, has become popular for treating canine lymphoma by providing longer survival times (MORRISON, 2004).
FDA previously approved Oncaspar in 1994 only for patients with ALL who were unable to receive the cancer drug L-asparaginase because they were allergic to that drug.
A gene encoding L-asparaginase was cloned from food-grade Aapergillus niger and expressed in its native host.
She developed severe hyperbilirubinemia secondary to the L-asparaginase.