CCBL1

(redirected from Kynurenine aminotransferase I)

CCBL1

A gene on chromosome 9q34.11 that encodes a cytosolic enzyme which metabolises cysteine conjugates of certain halogenated alkenes and alkanes, resulting in nephrotoxic and neurotoxic reactive metabolites.

Molecular pathology
Increased levels of CCBL1 have been anecdotally linked to schizophrenia.
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References in periodicals archive ?
Li, "pH dependence, substrate specificity and inhibition of human kynurenine aminotransferase I," European Journal of Biochemistry, vol.
Lubec, "Increased kynurenic acid levels and decreased brain kynurenine aminotransferase I in patients with Down syndrome," Life Sciences, vol.