Kyasanur Forest disease


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Related to Kyasanur Forest disease: Kyasanur Forest disease virus, KFD

Kyasanur Forest disease

 [ki-ah´sah-no̳r for´est]
a highly fatal viral disease of monkeys in the Kyasanur Forest of India, communicable to humans, in whom it produces a type of hemorrhagic fever.

Ky·as·a·nur For·est dis·ease

an arthropod-borne viral fever affecting forest workers in the Kyasanur Forest and in Mysore, India, caused by a Flavivirus in the family Flaviviridae. It is transmitted chiefly by Haemaphysalis spinigera, although other ticks have been implicated. Symptoms include fever, headache, back and limb pains, diarrhea, and intestinal bleeding; no central nervous system symptoms occur.
A tick-borne flaviviral haemorrhagic fever occurring in the Mysore and Karnataka states of India, maintained by infected monkeys and rodents; those living in wooded farmlands are at increased risk
Vector Haemaphysalis spinigera, a forest tick
Lab Leukopaenia, thrombocytopaenia, albuminuria
Dx Isolation of virus from blood, CF
Prognosis 5-10% mortality
Prevention Vaccine, protective clothing, tick control
Management None

Kyasanur forest disease

An ARBOVIRUS haemorrhagic fever that occurs in Mysore State, India, in the villages around the Kyasanur forest. The disease is caused by a virus of the same group as that causing JAPANESE B ENCEPHALITIS and the infection is transmitted by tick bite. There is sore throat, headache, muscle aches, abdominal pain and diarrhoea and the condition may progress to brain inflammation (ENCEPHALITIS).
References in periodicals archive ?
Diagnosis of Kyasanur Forest disease by nested RT-PCR, real-time RT-PCR and IgM capture ELISA.
Serological response to formalized Kyasanur Forest disease virus vaccine in humans at Sagar and Sorab Talukas of Shimoga district.
The low genetic distance between the Egypt and Saudi Arabia sequences supports the hypothesis of a recent divergence from Kyasanur Forest disease virus, i.e., the closest flavivirus (5), and a slow microevolution of ALKV, as for other tick-borne flaviviruses (13).
Kyasanur forest disease. In: Mishra A, Polasa H, editors.
Kyasanur forest disease: an epiderniological view in India.
When first described in 1957, Kyasanur Forest disease was restricted to a much smaller area (300 square miles) in India than the actual 2,000 square miles of endemic zone (10).
Previous studies have determined that AHFV is a variant genotype of Kyasanur Forest disease virus, another biosafety level (BSL) 4 virus that causes viral hemorrhagic fever in certain regions of India (3).
However, human modification to natural wildlife habitats and human behavior, such as deforestation, which causes range expansion of the tick vector for Kyasanur Forest disease in India, also create opportunities for emergence of zoonotic diseases.
LIV is included in the tickborne encephalitis virus (TBEV) complex that includes Kyasanur Forest disease virus and Alkhurma virus.