Kyasanur Forest disease virus

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Ky·as·a·nur For·est dis·ease vi·rus

a group B arbovirus, in the family Flaviviridae, isolated from monkeys in India and capable of causing Kyasanur Forest disease in humans; the virus is spread by monkeys and birds having mild infections; the vectors are probably species of the tick Haemaphysalis.
References in periodicals archive ?
Transmission of Kyasanur Forest disease virus by the soft tick Ornithodoros crossi.
The low genetic distance between the Egypt and Saudi Arabia sequences supports the hypothesis of a recent divergence from Kyasanur Forest disease virus, i.
Reaction of Rattus rattus wroughtoni to Kyasanur forest disease virus.
The reaction of Funambulus tristriatus, Rattus blanfordi and Suncus murinus to Kyasanur forest disease virus.
The closely related Kyasanur Forest disease virus, which is endemic in certain regions of India, is the only tickborne hemorrhagic fever virus that has been isolated from Ornithodoros spp.
The term "viral hemorrhagic fever" characterizes a severe multisystem syndrome associated with fever, shock, and bleeding diathesis caused by infection with any of several RNA viruses, including Ebola virus and Marburg virus (MARV) (family Filoviridae); Lassa virus (LASV) and the South American hemorrhagic fever viruses Guanarito virus, Junin virus, Machupo virus, and Sabifi virus (Arenaviridae); Rift Valley fever virus (RVFV), Crimean-Congo hemorrhagic fever virus (CCHFV), and hantaviruses (Bunyaviridae); and Kyasanur Forest disease virus (KFDV), Omsk hemorrhagic fever virus, yellow fever virus (YFV), and dengue viruses (Flaviviridae) (1,2).
Sensitivity of detection with synthetic RNA standards Pathogen * Detection threshold (RNA copies) ([dagger]) ZEBOV 20 SEBOV 20 MARV 20 LASV 20 RVFV 20 CCHFV 50 HNTV 20 SEOV 50 YFV 20 KFDV 20 * ZEBOV, Ebola Zaire virus; SEBOV, Ebola Sudan virus; MARV, Marburg virus; LASV, Lassa virus; RVFV, Rift Valley fever virus; CCHV, Crimean-Congo hemorrhagic fever virus; HNTV, Hantaan virus; SEOV, Seoul virus; YFV, yellow fever virus; KFDV, Kyasanur Forest disease virus.
Alkhurma hemorrhagic fever virus (genus Flavivirus, AHFV) was recently identified as the agent of a viral hemorrhagic fever in Saudi Arabia and characterized serologically and genetically as a variant genotype of Kyasanur Forest disease virus (KFDV).
AHFV was identified as a flavivirus on the basis of immunofluorescence assay performed with the flavivirus-specific monoclonal antibody 4G2 and polymerase chain reaction (PCR) amplification of a 220-bp genome fragment that exhibited 89% nucleotide (nt) sequence homology with the Kyasanur Forest disease virus (KFDV) NS5 gene.
We found no published reports describing a hemorrhagic disease caused by TBEV, although hemorrhagic manifestation is typical for tick-borne flaviviruses, including Omsk hemorrhagic fever virus (OHFV), Alkhurma virus, and Kyasanur Forest disease virus (9).