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Related to Kwell: Navane, permethrin, scabies, Elimite


the gamma isomer of benzene hexachloride, used as a topical treatment for lice and scabies.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.


Hexit Lotion (CA), Hexit Shampoo 1 (CA), PMS-Lindane LOT 1 (CA), PMS-Lindane SHP 1 (CA)′

Pharmacologic class: Chlorinated hydrocarbon

Therapeutic class: Scabicide, pediculocide

Pregnancy risk category C

FDA Box Warning

• Use only in patients who can't tolerate or have failed first-line treatment with safer drugs.

• Seizures and deaths have occurred with repeat or prolonged application, and in rare cases after a single application used as directed. Use cautiously in infants, children, elderly patients, persons with other skin conditions, and in those weighing less than 110 lb (50 kg).

• Drug is contraindicated in premature infants and patients with uncontrolled seizure disorders.

• Instruct patient about proper drug use, amount to apply, how long to leave it on, and importance of avoiding retreatment.


Absorbed through parasitic ova and arthropods, which stimulates parasitic nervous system and results in seizures and death of parasite


Lotion: 1%

Shampoo: 1%

Indications and dosages

Secondary treatment of scabies

Adults and children: Apply enough lotion on dry skin to cover entire surface from neck down. Rub in well, and leave in place 12 hours. Then wash skin thoroughly.

Secondary treatment of Pediculosis capitis (head lice) or Pediculosis pubis (pubic lice)

Adults and children: Apply enough shampoo to dry hair (1 oz or less for short hair, 1½ oz for medium length hair, up to 2 oz for long hair) to thoroughly wet hair and skin or scalp of affected and surrounding hairy areas. Leave in place 12 hours. Then wash hair thoroughly.


• Hypersensitivity to drug or its components

• Seizure disorder

• Crusted (Norwegian) scabies and other conditions that may increase systemic drug absorption

• Premature neonates


Use cautiously in:

• conditions that increase seizure risk (such as history of seizures, head injury, AIDS)

• skin conditions

• concurrent use of skin creams, oils, or ointments

• patients weighing less than 50 kg (110 lb)

• elderly patients

• breastfeeding patients

• infants or children.


• To apply, wear gloves made of nitrile, latex with neoprene, or sheer vinyl.

• Before applying lindane shampoo, use regular shampoo without conditioner; rinse and dry hair completely. Wait 1 hour before using lindane shampoo.

• Don't use lindane lotion or shampoo with other lotions, creams, or oils.

• Thoroughly wash skin after lotion has been in place for 12 hours.

Adverse reactions

CNS: dizziness, seizures, headache, anxiety, paresthesia

EENT: irritation of eyes, nose, and throat (from vapor inhalation)

GI: nausea and vomiting (from vapor inhalation)

Hematologic: aplastic anemia (with prolonged use)

Skin: dermatitis, urticaria, pruritus, alopecia

Other: pain


Drug-drug. Drugs that lower seizure threshold, antidepressants: increased seizure activity

Patient monitoring

• Monitor drug efficacy.

Patient teaching

Emphasize that drug is for external use only, and that ingesting even small amounts can be fatal.

• If drug will be applied by another person, tell patient that this person must wear gloves made of nitrile, latex with neoprene, or sheer vinyl.

• Instruct patient using lindane lotion to wash, rinse, and dry skin well before applying lindane if skin has cream, lotion, ointment, or oil on it. If he takes a warm bath or shower before applying lindane, instruct him to let skin dry and cool down. Then tell him to apply lindane to dry skin, rub in well, leave on skin for 8 to 12 hours, and then remove it by washing thoroughly.

• Instruct patient using lindane shampoo to apply enough shampoo to dry hair to thoroughly wet the hair and skin or scalp of affected and surrounding hairy areas, and then rub shampoo thoroughly into hair and skin or scalp and let it sit for 4 minutes. Then tell him to add just enough water to work up a good lather, then rinse thoroughly and dry hair with clean towel. When hair is completely dry, instruct him to comb it with a fine-toothed comb to remove any remaining nits or nit shells. Tell him not to use shampoo in combination with oils, lotions, or creams.

• To avoid reinfestation, instruct patient to launder all recently worn or used clothing, bed linens, and towels in hot water.

• Caution patient to avoid contact with eyes when applying lotion or shampoo.

• Tell patient with scabies that sexual contacts and other close personal contacts should be examined and, if necessary, treated.

• Advise female patient to inform prescriber if she plans to breastfeed.

• As appropriate, review all other significant and life-threatening adverse reactions and interactions, especially those related to the drugs mentioned above.

McGraw-Hill Nurse's Drug Handbook, 7th Ed. Copyright © 2013 by The McGraw-Hill Companies, Inc. All rights reserved


An isomer of the chlorocarbon C6H6Cl6, obtained as a white crystalline powder and having a musty odor. A potent pesticide, it has been banned from agricultural use in several countries including the United States, but is used topically in the treatment of scabies and pediculosis. Also called gamma benzene hexachloride.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.


Toxicology The γ-isomer of benzene hexachloride; a carcinogenic, lipid-soluble insecticide used topically to control lice and scabies, and occasionally for suicide; 20-30 g produce serious toxicity or death Clinical Onset is similar to DDT poisoning–tremors, ataxia, violent tonic-clonic convulsions, pulmonary edema and vascular collapse of neurogenic origin; massive hepatic necrosis ensues, accompanied by hyaline degeneration of renal tubules, aplastic anemia
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.


A benzene compound that is used to kill body and pubic lice. Lindane works by being absorbed into the louse's central nervous system, causing seizures and death.
Mentioned in: Lice Infestation
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.
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It is Ant and Dec's cheeky banter that would help to ease the pain of flying for most Brits, as the research, commissioned by travel sickness tablets Kwells showed that UK travellers favour wit and conversation over good looks.
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The makers of travel sickness products, Kwells, has issued advice on how to avoid motion sickness.
Hyoscine (Kwells) tablets can be taken at least 30 minutes before getting on the boat.
Superbly filmed and sufficiently in the moment to have you reaching for the Kwells, constant setbacks eventually meant them being so far behind schedule Lenny had to leave Bullimore to finish the trip alone, but it does seem to have cured his machismo.
Reaching - if you'll pardon the expression - for the Kwells? Wondering where your land legs have gone?
Try Boots Travel Calm Tablets, for pounds 1.79, Kwells for pounds 2.05, Sea Legs for pounds 2.05 or Joy Rides (for children) at pounds 2.10.
TREAT IT: Crystallised ginger, which research shows fights nausea, or try Kwells Travel Sickness Tablets (pounds 2.39, Lloyds pharmacy).
PACK IT: Kwells Travel Sickness Tablets, pounds 2.57.
Kwells Kids (pounds 2.25 for 12 tablets, chemists) These tiny tablets contain a
Additionally, there are medicines that can be taken to prevent travel sickness including Kwells, which also come in a junior version.
Your pharmacist should be able to give you advice about which of the travel sickness remedies - such as Kwells or Joy-Rides - are best for you.