arthrogryposis

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arthrogryposis

 [ahr″thro-grĭ-po´sis]
1. persistent flexion of a joint.
2. tetanoid spasm.

ar·thro·gry·po·sis

(ar'thrō-gri-pō'sis),
Congenital defect of the limbs characterized by severe contractures of multiple joints.
[arthro- + G. gryphōsis, a crooking]

arthrogryposis

(är′thrə-grə-pō′sĭs)
n. pl. arthrogrypo·ses (-sēz)
The permanent fixation of a joint in a contracted position.

arthrogryposis multiplex congenita

A rare sporadic condition characterised by joint contractures, dislocations, rigid skeletal deformities (e.g., clubfoot or talipes equinovarus), skin atrophy and replacement of limb muscles with fibrous tissue. AMC is not a sui generis disease, but rather a descriptive term that signifies multiple congenital contractures. The aetiologies encompass both neurogenic and primary myopathic diseases, but most cases are not due to neuromuscular disease.
 
Pathogenesis
Uncertain; a common link may be intrauterine movement during a critical period of limb development.
 
Management
Arthrodesis.

ar·thro·gry·po·sis

(ahr'thrō-gri-pō'sis)
Congenital defect of the limbs characterized by contractures of multiple joints.
[arthro- + G.gryphōsis, a crooking]

arthrogryposis

Congenital fixation of the limb joints, usually in an extended position. The condition is probably due to a destructive disorder of the motor nerves to the muscles around the affected joints during the pregnancy.