Kurtzke Expanded Disability Status Scale


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Kurtzke Expanded Disability Status Scale

(kŭrts′kē)
A widely used scale for measuring the functional status of people with multiple sclerosis. Ratings on eight systems (pyramidal, cerebellar, brainstem, sensory, bowel and bladder, visual, mental, and other) provide a combined disability score.
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An interim analysis of a Phase I/II dose-escalation study of six evaluable patients, half of whom received a low dose (six to nine million MRTCs) and the other half received a mid dose (30-45 million MRTCs) during the six-month evaluable period, indicated that the Tovaxin(TM) therapy reduces peripheral blood MRTC levels in concert with improvements in disability scores Kurtzke Expanded Disability Status Scale (EDSS) as well as in disability neurological assessments for psychological scores Multiple Sclerosis 29 point Impact Scale (MSIS-29).