Kupffer cells


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Kupf·fer cells

(kūp'fĕr),
phagocytic cells of the mononuclear phagocyte series found on the luminal surface of the hepatic sinusoids.

Kupf·fer cells

(kup'fĕr selz)
Phagocytic cells of the mononuclear phagocyte series found on the luminal surface of the hepatic sinusoids.

Kupffer cells

Fixed MACROPHAGE cells that line the fine blood sinuses (capillaries) of the liver and act as scavengers to remove senescent red blood cells, bacteria and other foreign material. (Karl Wilhelm von Kupffer, 1829–1902, German anatomist)

Kupffer,

Karl W. von, German anatomist, 1829-1902.
Kupffer cell sarcoma
Kupffer cells - phagocytic cells of the mononuclear phagocyte series found on the luminal surface of the hepatic sinusoids. Synonym(s): stellate cells of liver
References in periodicals archive ?
Su, "Lipopolysaccharides in liver injury: molecular mechanisms of Kupffer cell activation," American Journal of Physiology-Gastrointestinal and Liver Physiology, vol.
Monocyte-derived (freshly infiltrating) macrophages are characterized as CD11b+ F4/80+ cells by FACS in mice, whereas matured monocyte-derived and resident Kupffer cells are [CD11b.sup.lo] F4/[80.sup.hi] [31].
Tiegs, "IL-10, regulatory T cells, and Kupffer cells mediate tolerance in concanavalin A-induced liver injury in mice," Hepatology, vol.
Kupffer cells are very good sources of mitogenic cytokines such as TNFa.
The rate of Kupffer cells in liver and ATM infiltration into adipose tissue was also decreased in the Euphorbia-treated group.
Fixed monocytes (Kupffer cells) were present in the lining of sinusoids (Fig.1).
Microscopically, hepatocytes were showed minimal degeneration, sinusoidal congestion and moderate multifocal aggregations of golden yellow coloured pigment in kupffer cells (Fig.
Besides DCs, intrahepatic Kupffer cells also participate in the anti-HBV immune response, partly through interfering with the NK cells.
Histoplasmosis features portal lymphohistiocytic inflammation and sinusoidal Kupffer cell hyperplasia, and organisms are generally present within both portal macrophages and Kupffer cells (Figure 8, A and B).35 Discrete granulomas and giant cells are seen in only a minority of cases.
Examples include Kupffer cells, macrophages residing in the liver, and microglia, residing in the central nervous system.
These changes were accompanied by swelling of Kupffer cells in congested sinusoidal ves-sels.16 The determination of transaminase activity in serum is a common means of detecting liver damage.
(2007) reported that a high-fat diet induced PS externalization on erythrocytes and erythrophagocytosis by Kupffer cells in the liver, resulting in inflammation and hepatic fibrosis.