Krebs-Ringer solution

Krebs-Ring·er so·lu·tion

(krebz ring'ĕr),
a modification of Ringer solution.
[Sir Hans Adolph Krebs, Sydney Ringer]
Farlex Partner Medical Dictionary © Farlex 2012


Sir Hans Adolph, German biochemist in England and Nobel laureate, 1900-1981.
Krebs cycle - together with oxidative phosphorylation, the main source of energy in the mammalian body and the end toward which carbohydrate, fat, and protein metabolism are directed. Synonym(s): tricarboxylic acid cycle
Krebs-Henseleit cycle - the sequence of chemical reactions, occurring primarily in the liver, that results in the production of urea. Synonym(s): urea cycle
Krebs-Ringer solution - a modification of Ringer solution.


Sydney, English physiologist, 1835-1910.
Krebs-Ringer solution - see under Krebs, Sir Hans Adolph
lactated Ringer injection - used intravenously as a systemic alkalizer and a fluid and electrolyte replenisher.
lactated Ringer solution - a sterile solution of calcium chloride, potassium chloride, sodium chloride, and sodium lactate in water. Synonym(s): Hartmann solution
Locke-Ringer solution - see under Locke
Ringer injection - a sterile solution of sodium chloride, potassium chloride, and calcium chloride, used intravenously as a fluid and electrolyte replenisher.
Ringer solution - resembles the blood serum in its salt constituents.
Medical Eponyms © Farlex 2012

Krebs-Ring·er so·lu·tion

(krebz ringĕr sŏ-lūshŭn)
Modification of Ringer solution.
Medical Dictionary for the Dental Professions © Farlex 2012
References in periodicals archive ?
The final dilution was made in Krebs-Ringer solution. The Krebs-Ringer solution had the following composition (mM) NaCl, 137; KCl, 3.7; Ca[Cl.sub.2], 1.02; Mg[Cl.sub.2], 0.05; Na[H.sub.2]P[O.sub.4], 0.32; NaHC[O.sub.3], 11.9; and glucose, 5.
Then, they were immediately placed in a Petri dish containing Krebs-Ringer solution bubbled with 100% oxygen.
The thorax was opened and the heart was carefully dissected and perfused through the aortic stump with Krebs-Ringer solution containing 118.4 mM NaCl, 4.7 mM KCl, 1.2 mM K[H.sub.2]P[O.sub.4], 1.2 mM MgS[O.sub.4] x 7[H.sub.2]O, 1.25 mM Ca[Cl.sub.2] x 2[H.sub.2]O, 11.7 mM glucose, and 26.5 mM NaHC[O.sub.3].
Extracellular dye was removed by repeated dilution of the sample in Krebs-Ringer solution. Then, the cells were incubated in a buffered salt solution appropriate for the experiments, that is, containing various concentrations of calcium or calcium free with or without EGTA added.
Krebs-Ringer solution (in mM): NaCl, 139; KCl, 5; Mg[Cl.sub.2], 1.2; Ca[Cl.sub.2], 2; glucose, 10; HEPES, 10 pH was adjusted to 7.4 by NaOH.
Krebs-Ringer solution (0.37mg/mL Ca[Cl.sub.2] X 2[H.sub.2]O, 0.35 mg/ mL KCl, 0.24 mg/mL Mg[Cl.sub.2]-6[H.sub.2]O, 0.19 mg/mL Na[H.sub.2]P[O.sub.4]2[H.sub.2]O, 6.84 mg/mL NaCl, 2.10 mg/mL NaHC[O.sub.3], and 1.98 mg/mL glucose) was prepared before each experiment.
The jejuna were washed with physiological saline and dipped in ice-cold Krebs-Ringer solution with [O.sub.2]/C[O.sub.2] (95/5, v/v).
The tissue bath was filled with Krebs-Ringer solution at 37 [degrees]C, with the following composition (mM): NaCl 118.3, KC1 4.7, [CaCl.sub.2] [2H.sub.2.O] 2.5, [MgSO.sub.4] [7H.sub.2]O 1.2, [KH.sub.2][PO.sub.4] 1.2, [NaHCO.sub.3] 25, D-Glucose 11.1, was bubbled with 95% [O.sub.2] and 5% [CO.sub.2] ([pO.sub.2] = 345 [+.or.-]8 mmHg), pH = 7.2.
The rings were then mounted in four-channel organ baths filled with Krebs-Ringer solution (pH 7.4): 115.5 mM NaCl, 4.6 mM KCl, 1.2 mM K[H.sub.2]P[O.sub.4], 1.2 mM MgS[O.sub.4], 2.5 mM Ca[Cl.sub.2], 25.0 mM NaHC[O.sub.3], and 11.1 mM glucose.
Abdomen was opened by midline incision and segments of distal ileum and proximal colon were dissected out quickly and cleaned by flushing out the intestinal content by fresh Krebs-Ringer solution. Thereafter, it was quickly placed in a Petri dish containing freshly prepared Krebs-Ringer solution bubbled with 100% oxygen.
We compared these actions to those observed when PCB 153 is dissolved in normal Krebs-Ringer solution and perfused on slices from control rats of the same age.
The specimens were transferred to a Petri dish containing ice-cold (4-6[degrees]C) oxygenated Krebs-Ringer solution and thoroughly cleaned with freshly prepared cold Ringer solution.