Also found in: Dictionary, Thesaurus, Encyclopedia.
Related to Krabbe's disease: Gaucher's disease
a familial form of leukoencephalopathy beginning in infancy, in which the sphingolipid ceramide galactoside accumulates in the tissues due to a deficiency of β-galactosidase, marked pathologically by cerebral demyelination and by the presence of large globoid bodies in the white substance.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
Krabbe's diseaseSee GLOBOID CELL LEUKODYSTROPHY.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005