Clinical profile of segmental vitiligo which included the age of the patient, gender, age at onset, duration of the disease at presentation, affected dermatome, family history, presence or absence of Koebner phenomenon
and the presence of associated diseases, was studied in these patients.
Upon clinical examination, both patients presented with flat-topped, purplish, itchy papules and linear lesions that appeared after days of scratching, compatible with the Koebner phenomenon
Mucosal involvement, leukotrichia, and Koebner phenomenon
were not observed in any of the patients.
Clinically; patients are first evaluated in terms of 12 features, including degree of scaling and erythema; presence or absence of defined lesion borders; itching and koebner phenomenon
; papule formation; family history; and involvement of the oral mucosa, knees, elbows, and scalp, which are important indices in the differential diagnosis of erythemato-squamous diseases.
Patients with PV (VIDA score over 2 points) showed emergence of new skin lesions expansion of the original skin lesions or occurrence of the Koebner phenomenon
within three months.
(1,5,6) While it is generally accepted that trauma may trigger LS via the Koebner phenomenon
(the appearance of lesions at the site of injury), there is debate as to whether microbes--especially Borrelia burgdorferi and human papillomavirus (HPV)--might play a role.
Vitiligo was reported around lips in a patient treated with isotretinoin owing to the chelitis as a Koebner phenomenon
. This patient suffered from vitiligo prior to the initiation of isotretinoin .
Patients will often exhibit the Koebner phenomenon
, where lesions arise at the sites of trauma exhibited by scratching .
Jolly, "Discoid lupus erythematosus after tattoo: Koebner phenomenon
," Arthritis & Rheumatism, vol.
This is similar to the Koebner phenomenon
, which is thought to be a factor in the formation of lichen sclerosus in the phimotic penis [17, 18].
Some cases have demonstrated concern for inducing the Koebner phenomenon
at sites of trauma with dilatation .
The first was self-reported information from patients, namely, demographic data (e.g., age, gender, weight, height, and income), family history of vitiligo, age of onset of vitiligo, initial location of the lesion, factors influencing the disease, Koebner phenomenon
(KP) type 1, disease activity, and dermatology life quality index (DLQI).