Koch's postulates(redirected from Koch postulate)
Also found in: Encyclopedia.
Koch's postulatesA series of 4 conditions that must be met to establish an infectious agent as the cause of a particular disease or condition. See Molecular Koch's postulates.
1. The agent must be present in all cases of the disease
2. The agent must be isolated from someone with the disease and grown in pure culture
3. Inoculation into a susceptible organism of the agent–from a pure culture—must produce the disease
4. The agent must be recovered from the infected–inoculated organism and grown again in culture
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
Koch's postulatesA set of criteria to be obeyed before it is established that a particular organism causes a particular disease. The organism must be present in every case and must be isolated, cultured and identified; it must produce the disease when a pure culture is given to susceptible animals; and it must be recoverable from the diseased animal. (Robert Koch, 1843–1910, German bacteriologist)
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005