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A type of targeted mutation in which an alteration in gene function is produced, usually a gain of function by adding or substituting genetic material.
Example Substitution of a mouse gene sequence for a human sequence
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25: Cruckton & District Ploughing & Hedging Society ploughing match, Hanley Hall, Knockin, Shropshire. Helen Davies, 01938 590535.
Jim has been a farrier for more than 25 years, following in his father's footsteps in Knockin, Shropshire.