knockout

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knock·out

, knock-out (nok'out, nok'-out),
A genetically engineered organism in which the genome has been altered by site-directed recombination so that a gene is deleted.
Farlex Partner Medical Dictionary © Farlex 2012

knockout

(nŏk′out′)
adj. also knock-out (nŏk′out′)
Genetics Having a specific single gene inactivated or removed by genetic manipulation: knockout mice used in an experiment.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
Experimental biology A genetically engineered mutant animal—e.g., Drosophila, mouse, fish, et al—in which a targeted gene has been inactivated to facilitate analysis of the knocked-out gene’s activity and function
Molecular medicine adjective Referring to the inactivation of a specific gene or genes noun A lab organism—e.g., yeast or mouse—in which a specific gene is altered, inactivating it and creating a model for a particular disease; in knockouts, an extracellular signal is converted to a functional intracellular change
Sports medicine KO The vanquishing of an opponent in a combat sport by bringing the opponent to the mat or ground. In boxing, this is defined as when the boxer is knocked down and cannot get up by the referee’s count of 10. A technical knockout (TKO) is one in which the referee or ringside doctor determines that the fighter is unable to defend himself or has sustained a serious injury, or when the fighter’s handlers throw in the towel
Vox populi Bombshell A woman who is stunningly beautiful
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

knock·out

, knock-out (nok'owt)
A genetically engineered organism in which the genome has been altered by site-directed recombination so that a gene is deleted.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

knockout

see GENE DISRUPTION.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005
References in periodicals archive ?
Ominously for his opponent in Liverpool he aims to deliver his most impressive knock-out tonight as he moves closer to a title shot.
"If we had gone all the way to the final it might have been increased, but the budget is set based on an exit from the first knock-out round.
It also absorbs and disperses the impact of a blow to this area of the head, protecting the brain from concussions and reducing the possibility of "knock-outs," severe neck injuries, or cerebral hemorrhage.
I am so proud that we qualified for the Abu Dhabi knock-outs, winning all our games.
With no pool format this time round, the top eight teams have been given a bye to Round of 16 with Kenya, seeded number nine facing off with 14 other teams in the pre-qualifying knock-outs on July 20 according to the scheduled released on Tuesday night by World Rugby.Kenya will face-off with Tonga for the right to play eighth seeded Scotland in the Round of 16 during the three-day Rugby World Cup Sevens set for the iconic ATandT Park in San Francisco, USA.
But Kashiwa, who earned their lead through Eduardo and Kosuke Taketomi's brace, held on to book their spot in the knock-outs and leave former winners Jeonbuk sweating.
"The cup knock-outs will have hit them hard and now the target will be to get into the Champions League places.
"His record has made him hard to match - no fighters who operate over four and six rounds want to take him after they look at his string of knock-outs.
"I don't just want to beat him, I want to finish him," said the 31-year-old Bellew (22 wins, two defeats and one draw, with 14 knock-outs).
Rising inflation expectations are one of three so-called "knock-outs" that could see the Bank break its pledge to keep rates at 0.5% until the unemployment rate drops to 7%.
"He's had more knock-outs than I've had fights and he didn't stop me.