In the Pediatric Rheumatology Unit of our tertiary care hospital, oral treatment is offered to children diagnosed with osteoarticular infection (OAI), acute hematogenous osteomyelitis (OM), and septic arthritis (SA) and with suspected Kingella kingae
As causes of epiphyseal osteomyelitis other than Mycobacterium species, Kingella kingae
, a Gram-negative bacterium, is the leading cause of bone and joint infections in early childhood [4,7].
Now, scientists are able to do a better job of identifying the germs that cause the infections, including the one that's the focus of the new study -- Kingella kingae
. For the study in the September 5 issue of CMAJ, researchers examined 77 kids in Canada and Switzerland.
is a facultative anaerobic, nonmotile, and fastidious [beta]-hemolytic Gram-negative coccobacilli.
* Distinguish anatomic sites of invasive Kingella kingae
was initially isolated by Elizabeth O.
, a short Gram negative bacillus, is best known for being a constituent of the HACEK group of organisms; i.e.
. Se considera que es el principal gram negativo productor de artritis septica; particularmente en menores de 3 anos, con antecedentes de cuadros respiratorios, sin embargo, los metodos diagnosticos de laboratorio y de aislamiento son deficientes en su deteccion (12,20-22).
An important and underappreciated cause of septic arthritis in non-neonates younger than age 5 years is Kingella kingae
. It is typically culture-negative but can be detected by polymerase chain reaction.
Using primers to detect the mecA and nuc genes of Staphylococcus aureus and the cpn60 target on the chaperon gene of Kingella kingae
, polymerase chain reaction (PCR) was performed using the purulent drainage obtained from the knee.
CHICAGO -- Consider Kingella kingae
as a cause of infection when diagnosing and treating children with suspected acute osteomyelitis, an infectious disease specialist advised.
is a fastidious gram-negative coccobacillus that colonizes the respiratory and oropharyngeal tract in children.