angiolymphoid hyperplasia with eosinophilia

(redirected from Kimura disease)

an·gi·o·lym·phoid hy·per·pla·si·a with e·o·sin·o·phil·i·a

solitary or multiple small benign cutaneous erythematous nodules, occurring mainly on the head and neck in young adults, characterized by dermal proliferation of blood vessels with vacuolated histiocytoid endothelial cells and with a varied infiltrate of eosinophils, lymphocytes which may form follicles, and histiocytes.
Synonym(s): Kimura disease
Farlex Partner Medical Dictionary © Farlex 2012

angiolymphoid hyperplasia with eosinophilia

An uncommon idiopathic condition with some features of Kimura disease, which presents in adults as one or more red-blue papules, plaques, or nodules in the head and neck, less commonly in the hands, shoulders, and elsewhere. It is unknown whether it is neoplastic or reactive.
Prognosis ALHE is clinically benign but persistent and treatment is refractory.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.


Tetsuji, 20th century Japanese pathologist.
Kimura disease - solitary or multiple small benign cutaneous erythematous nodules. Synonym(s): angiolymphoid hyperplasia with eosinophilia
Medical Eponyms © Farlex 2012
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References in periodicals archive ?
The differential diagnosis of EAF is broad and includes reactive conditions (granulomatosis with polyangiitis, Churg-Strauss syndrome, Kimura disease, angiolymphoid hyperplasia with eosinophilia, granuloma faciale, erythema elevatum diutinum), and neoplastic lesions (angiofibroma, schwannoma, fibroma, fibromatosis).
Kimura disease (KD), which is one of the most difficult clinical entities concerning the diagnosis, is a rare, benign, chronic inflammatory disease with unknown etiology.
Table 1: Distinguishing clinicopathological features of Angiolymphoid Hyperplasia with Eosinophilia and Kimura Disease.
Although AHE might mimic superficial form of Kimura disease and the coexistence of the two entities has been reported,11 they are presently considered to be separate entities: AHE lesions are localized in the superficial tissues, while Kimura disease involves deeper tissues such as lymph nodes and salivary glands.12,13
This lesion does not involve lymph nodes (i.e., not Kimura disease).
Kimura disease is a rare idiopathic inflammatory disease that presents as painless nodules and masses in the head and neck region.
Kimura disease: a clinopathologic study of 21 cases.
(2004) Kimura disease: a clinicopathological study of 21 cases.
The major differential diagnosis lies between ALHE/EH and Kimura disease. In the past, ALHE/EH and Kimura disease were thought to be the same entity.
Angiolymphoid hyperplasia with eosinophilia and Kimura disease. In: Wolff K, Goldsmith LA, Katz SI et al.
Kimura disease is an uncommon chronic, benign, inflammatory condition of unknown etiology.
INTRODUCTION: Kimura Disease (KD) is a rare chronic inflammatory disorder, which was first described in 1937 by Kim and Szeto in the Chinese literature as "eosinophilic hyperplastic lymphogranuloma" and has been known most often as Kimura's disease since its description by Kimura et al.