Killip scale

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Killip scale

Killip classification Cardiology A system used to stratify the severity of left ventricular dysfunction and determine clinical status of Pts post MI
Killip classification
Class 1 No rales, no 3rd heart sound
Class 2 Rales in <12 lung field or presence of a 3rd heart sound
Class 3 Rales in >12 lung field–pulmonary edema
Class 4 Cardiogenic shock–determined clinically
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
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At admission, patients who had a history of beta blockers, angiotensin-converting-enzyme (ACE) inhibitors and angiotensin II receptor blockers(ARBs) for the treatment of hypertension, had longer symptom time and had higher Killip classification developed AKI during the hospital stay.
In multivariate models, covariates included age [greater than or equal to] 65, male, smoking history, hypertension, diabetes, Killip classification [greater than or equal to] 3, the left anterior descending artery (LAD) as the IRA, neutrophil count [greater than or equal to] 9.14 x [10.sup.9]/L, neutrophil/lymphocyte ratio, cardiac troponin I (cTNI), upfront intracoronary GPIIb/IIIa receptor inhibitor administration, aspiration thrombectomy, platelet counts, white blood cell (WBC) counts, hemoglobin (HGB), time from symptom onset to reperfusion (>6 hours), multi-vessel disease, and initial TIMI flow grade (0-1) (those with a P value < 0.1 in univariate analysis and those that were clinically relevant).
In univariate analysis, the Killip classification [greater than or equal to] 3 (OR =2.824, 95% CI: 1.155-6.904, P = 0.023), LAD as the IRA (OR= 1.821, 95% CI: 1.018-3.259, P = 0.043), neutrophil count [greater than or equal to] 9.14 x [10.sup.9]/L (OR = 2.880, 95% CI: 1.573-5.275, P = 0.001), neutrophil/ lymphocyte ratio (OR= 1.067, 95% CI: 1.015-1.121, P = 0.011), cTNI (OR= 1.004, 95% CI: 1.000-1.008, P = 0.036), and WBC count (OR= 1.086, 95% CI: 1.002-1.178, P = 0.046) were predictors for no-reflow.
In univariate and multivariate logistic regression analyses, a neutrophil count above 9.14 x [10.sup.9]/L was independently associated with no-reflow after adjusting for age [greater than or equal to] 65, male, smoking history, hypertension, diabetes, Killip classification [greater than or equal to] 3, LAD as the IRA, neutrophil/lymphocyte ratio, cTNI, upfront intracoronary GPIIb/IIIa inhibitor administration, aspiration thrombectomy, platelet counts, WBC counts, HGB, time from symptom onset to reperfusion (>6 hours), multivessel disease, and initial TIMI flow grade (0-1).
Additionally, other factors that are clinically relevant to no-reflow including hypertension, blood pressure, Killip classification ([greater than or equal to] 3), cTNI, time from symptom onset to reperfusion (>6 hours), multivessel disease, and initial TIMI flow grade (0-1) were also included in the multivariate analysis in the present study.
Age, sex, BMI, prevalence of diabetes mellitus, hyperlipidemia, hypertension, smoking, obesity and Killip classification were not different between the patients with and without new cardiac events.
As mentioned above, age, sex, BMI, prevalence of diabetes mellitus, hyperlipidemia, hypertension, smoking, obesity and Killip classification were not different between the patients with and without new cardiac events.
On final logistic regression analysis, after adjusting for baseline variables, the following variables were independent predictors of fQRS: Coronary artery narrowing (P = 0.035), Killip classification (P = 0.026), and total cholesterol (P = 0.002).
On final logistic regression analysis, after adjusting for baseline variables, the number of narrowed coronary arteries (odds ratio [ OR ]: 1.236; 95% confidence interval [ CI ]: 1.015–1.507; P = 0.035), Killip classification ( OR : 1.667; 95% CI : 1.062–2.618; P = 0.026), total cholesterol ( OR : 1.357; 95% CI : 1.116–1.650; P = 0.002) were all independent predictors of fQRS [Table 4].{Table 4}
The number of narrowed coronary arteries, Killip classification, and total cholesterol are all independent predictors of the fQRS complexes.
Additionally, we found the fQRS group to be associated with more numbers of narrowed coronary arteries; higher Killip classifications, higher total cholesterol levels, and increased rates of recurrent angina.