Kikuchi disease

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Ki·ku·chi disease

necrotizing lymphadenitis of unknown etiology characterized by lymph node enlargement, associated with fever that subsides spontaneously. Most often seen in young women in Japan but appears in other countries.
Farlex Partner Medical Dictionary © Farlex 2012

Kikuchi disease

A rare, idiopathic lesion of young women, which is characterised by painful localised, usually cervical, lymphadenopathy. 

Clinical findings
Fever or upper-respiratory tract symptoms, weight loss, nausea, vomiting, night sweats.

Increased interferon-gamma, IL-6 , FasL in acute phase, anti-nuclear antibodies, elevated ESR; 50% of cases have a mild reduction in neutrophils and increase in lymphocytes. 

Benign, self-limited; usually resolves in 1 to 4 months.
Note: Some authors regard Kikuchi’s disease as a forme fruste of systemic lupus erythematosus.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

Ki·ku·chi dis·ease

(ki-kū'chē di-zēz')
Necrotizing lymphadenitis of unknown etiology, most often encountered in young women in Japan but also in other parts of the world; lymph node enlargement, associated with fever; subsides spontaneously.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive ?
Kikuchi-Fujimoto disease was first described (4,5) in Japanese patients and has a higher prevalence among Asians.
On the basis of history, examination findings and investigations, patient was diagnosed as a case of Kikuchi-Fujimoto disease.
Kikuchi-Fujimoto disease is also a rare but benign disease that typically presents with cervical lymphadenopathy, fever, and a flu-like presentation.
Kikuchi-Fujimoto disease should be considered in every child with fever of unknown origin and lymphadenopathy if other infectious, autoimmune and malignant causes were excluded.
On the basis of these morphological and immunophenotype findings, a diagnosis of Kikuchi-Fujimoto disease was made.
Kikuchi-Fujimoto Disease: A Rare Presentation with Localized Iliac Lymphadenitis.
Keywords: Kikuchi-Fujimoto Disease, Cervical lymphadenopathy, Lymph nodes.
Kikuchi-fujimoto disease, a rare clinicopathological entity, is a benign self-limiting disease, first described in 1972 by Kikuchi and Fujimoto in Japan independently.
Kikuchi-Fujimoto disease (KFD) is histiocytic necrotizing lymphadenitis, first described by Dr Masahiro Kikuchi in 1972 in Japan.
Is human herpesvirus 6 linked to Kikuchi-Fujimoto disease? The importance of consistent molecular and serologic analysis.