Kikuchi diseaseA rare, idiopathic lesion of young women, which is characterised by painful localised, usually cervical, lymphadenopathy.
Fever or upper-respiratory tract symptoms, weight loss, nausea, vomiting, night sweats.
Increased interferon-gamma, IL-6 , FasL in acute phase, anti-nuclear antibodies, elevated ESR; 50% of cases have a mild reduction in neutrophils and increase in lymphocytes.
Benign, self-limited; usually resolves in 1 to 4 months.
Note: Some authors regard Kikuchi’s disease as a forme fruste of systemic lupus erythematosus.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
Kikuchi's diseaseA disease usually affecting young women who present with painless enlarged lymph nodes in the neck or elsewhere, fever and liver damage. The condition may be confused with malignant LYMPHOMA or HODGKIN'S DISEASE but usually settles within three months.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005