ketolide


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ketolide

(kē-tō-līdz'),
Member of a class of antimicrobial agents related to macrolides.

ketolide

(kē′tō-līd″)
A derivative of the macrolide antibiotics, modified by the addition of a ketone to the macrolide structure. Telithromycin is a ketolide.
References in periodicals archive ?
Resistance to macrolide, lincosamide, streptogramin, ketolide, and oxazolidinone antibiotics.
50] and leakage of marker enzymes for drugs from macrolide and ketolide series and further comparison of [IC.
The newer classes of streptogramins (Synercid[R]) and oxazolidinones (Zyvox[R]), both used to treat drug resistant staphylococcal infections, also work by inhibiting protein synthesis, as does the new ketolide, telethromycin (Bryskier, 2005c.
The ketolide antibiotic remains approved for treatment of mild to moderate community-acquired pneumonia (CAP) in patients aged 18 and over.
48) found that in vivo drug disposition of ABT-773, a ketolide antibiotic that is a substrate for both CYP3A and P-glycoprotein, depends on the CYP3A5, but not the MDR1 genotype.
azithromycin, erythromycin, or any other macrolide or ketolide antibiotic.
Telithromycin (HMR 3647) is a new ketolide antimicrobial that was developed for the treatment of community-acquired respiratory truer infections.
Results from the Prospective Resistant Organism Tracking and Epidemiology for the Ketolide Telithromycin (PROTEKT US) surveillance study, covering isolates collected during 2000-2004, indicate that the prevalence of mef(A) is decreasing, and isolates harboring erm(B) and mef(A) genes are becoming increasingly common (13).
SAN FRANCISCO -- Clinical signs and symptoms of acute bacterial exacerbation of chronic bronchitis improved in patients treated with 5 days of an experimental ketolide antibiotic, cethromycin, or 7 days of levofloxacin, David A.
Objective: Telithromycin, the first approved ketolide antibiotic, was developed to treat community-acquired respiratory tract infections, including acute bacterial maxillary sinusitis (ABMS).
erythromycin or any macrolide or ketolide antibiotic should not take