Kawamura K, Kasukabe H, Barrie L (1996) Source and reaction pathway of dicarboxylic acids, ketoacids
and dicarbonyls in Artic aerosols: One year of observation.
These are caused by methyl ketones produced from the thermal degradation of ketoacids
in milkfat triglycerides and by different sulfur compounds.
The breakdown of fat leads to the production of ketones, or ketoacids
, as byproducts.
Other substances, such as serum proteins, ketoacids
, and drugs (cephalosporins and cimetidine) also react with pierate under these conditions, potentially overestimating the creatinine level by as much as 20% [17, 18].
Unconsciousness with the presence of Glucose and ketoacids
Very low protein diets must be accompanied by supplements of essential amino acids and ketoacids
Accumulation of ketoacids, which occurs through an alteration of the normal metabolic pathways, results in metabolic acidosis.
However, urinary excretion of ketones cannot keep up with the production of these ketoacids, and acidosis increases.
Cysteine first reacts with ketoacids
to form 3-mercaptopyruvate via the catalytic action of cysteine aminotransferase (CAT; EC 2.
The presence of high salt concentrations; fluorescein (168); carbonyl compounds (169), in particular acetoacetic acid and ketoacids
(170); glucose (171); and several drugs (172), including dopamine (173), cephalosporins (174, 175), and trimethoprim (176), cause a moderate to high increase in creatinine concentration.