FGF7

(redirected from Keratinocyte Growth Factor)
Also found in: Acronyms, Wikipedia.

FGF7

A gene on chromosome 15q21.2 that encodes fibroblast growth factor 7 of the FGF family, which bind heparin and have a broad range of cellular activities, including cell survival, division, differentiation and migration, embryonic development, morphogenesis, tissue repair, tumour growth and invasion. FGF7 is a potent epithelial cell-specific growth factor, which is mitogenic for keratinocytes, but has little effect on fibroblasts; it is required for normal branching morphogenesis. FGF7 interacts with FGF2 receptor (FGFR2).
References in periodicals archive ?
Supplementing the keratinocyte growth factor and co culturing a combination of fibroblast and keratinocyte cells on chitosan scaffold may help in faster wound healing in cases of burn cases with no scar formation.
Although the keratinocyte growth factor receptor has been reported to be absent on cells of the hematopoietic lineage, it is present on epithelial cells in many other tissues.
Androgen receptor activation in prostatic tumour cell lines by a insulin-like growth factor-1, keratinocyte growth factor, and epidermal growth factor.
Keratinocyte growth factor is upregulated by hyperplasia-inducing drug nifedipine.
Androgen receptor activation in prostatic tumor cell lines by insulin-like growth factor-I, keratinocyte growth factor, and epidermal growth factor.
Danilenko et al investigated recombinant epidermal growth factor, keratinocyte growth factor, platelet-derived growth factor-BB, and neu differentiation factor.
For instance, certain growth factors, such as insulin-like growth factor-1, keratinocyte growth factor, and epidermal growth factor (EGF), as well as HER2/ neu, a member of the EGF-receptor family of receptor tyrosine kinase, can activate AR-dependent genes in absence of AR ligand (Culig et al.