KRT5

(redirected from Keratin 5)
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KRT5

A gene on chromosome 12q13.13 that encodes a type-II cytokeratin that is specifically co-expressed in the basal layer of the epidermis with family member KRT14.

Molecular pathology
KRT5 mutations are associated with epidermolysis bullosa simplex.
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References in periodicals archive ?
The disorder is due to gene defects that result in a lack of one or both of two of these proteins, keratin 5 (K5) and keratin 14 (K14).