keratan sulfate

(redirected from Keratan sulphate)

keratan sulfate

 [ker´ah-tan]
either of two sulfated mucopolysaccharides (I and II). Keratan sulfate is an important component of the proteoglycan of cartilage, and occurs in the cornea and the nucleus pulposus, and is also an accumulation product in Morquio's syndrome.

ker·a·tan sul·fate

(ker'ă-tan sŭl'fāt),
A type of sulfated mucopolysaccharide containing d-galactose in place of the uronic acid of hyaluronic acid or chondroitin; also containing unsulfated and 6-sulfated N-acetyl-d-glucosamine; found in cartilage, bone, connective tissue, the cornea, aorta, and in the intervertebral disks; accumulates in Morquio syndrome; keratan sulfate I is abundant in cornea and is attached to a protein via an asparaginyl residue; keratan sulfate II is found in loose connective tissue and bone and is linked to a seryl or threonyl residue.
Synonym(s): keratosulfate

keratan sulfate

/ker·a·tan sul·fate/ (ker´ah-tan) either of two glycosaminoglycans (I and II), consisting of repeating disaccharide units of N -acetylglucosamine and galactose, but differing slightly in carbohydrate content and localization. It occurs in cartilage, the cornea, and in the nucleus pulposus and is also an accumulation product in Morquio's syndrome.

keratan sulfate

(kĕr′ə-tăn′)
n.
Any of several glycosaminoglycans found especially in the cornea, cartilage, and bone.

ker·a·tan sul·fate

(ker'ă-tan sŭl'fāt)
A type of sulfated mucopolysaccharide found in cartilage, bone, connective tissue, the cornea, aortae, and in the intervertebral discs; accumulates in Morquio syndrome.
Synonym(s): keratosulfate.

keratan sulfate

a glycosaminoglycan which exists as either of two sulfated mucopolysaccharides (I and II). Keratan sulfate is an important component of the proteoglycan of cartilage, and occurs in the cornea and the nucleus pulposus.
References in periodicals archive ?
The major classes of GAG include hyaluronic acid (HA), heparin sulphate, heparin, chondroitin 4-sulphate, chondroitin 6-sulphate, dermatan sulphate and keratan sulphate.
1) (2) They both recognised the occurrence of corneal clouding, aortic valve disease and urinary excretion of keratan sulphate.