Kepone


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Kepone

 [ke´pōn]
trademark for a polychlorinated ketone used as an insecticide; workers exposed to this nonbiodegradable compound have suffered neurologic symptoms, such as tremors and slurred speech.

Kepone

/Ke·pone/ (ke´pōn) trademark for a nonbiodegradable polychlorinated ketone, used as an insecticide; workers exposed to it have suffered neurologic symptoms such as tremors and slurred speech.
A carcinogenic chlorinated polycyclic ketone insecticide and fungicide used in the US between 1966 and 1975. It gained notoriety from its improper handling and dumping into the James River, Virginia, which was subsequently closed to fishing. Chlordecone has a 30-year environmental half-life
Toxicity Tremors, nystagmus, memory loss, headaches, slurred speech, unsteadiness, incoordination, loss of weight, rash, hepatomegaly, decreased libido, sterility, chest pain, arthralgia, and the increased risk of cancer
References in periodicals archive ?
4-n-NP), diadzein (Dai), genistein (Gen), kaempferol (Kaem), apigenin (Api), coumestrol (Coum), endosulfan (Endo), kepone (Kep), and 1-bromopropane (1-BP) were obtained from the Midwest Research Institute (Kansas City, MO) through a contract with the National Toxicology Program and are previously described (Li et al.
On the issue of importing toxic waste from the US, a diplomat wrote: "EPA (the Environmental Protection Agency) has requested Department's assistance in confirming Allied Chemical Corporation contention that the UK Government has been informed of the trial incineration of 80 drums of Kepone scheduled to be performed by Rechem International Ltd, Pontypool, Wales.
The exhibition took place in the presence of the European Union Ambassador's Representative, Marcelo Mori, Swedish Ambassador to Lebanon, Nicholas kepone, and scores of concerned dignitaries.
Our area is no longer in a crisis (or perceived crisis) that causes it to take priority over other more pressing national problems such as terrorism and the financial crisis--as it once was when the Cuyahoga River caught fire, Kepone poisoned the James River, children in the inner city suffered retardation from lead in gasoline, and we believed that PCBs and other chlorinated organics were causing wide-spread sterility in the animal kingdom and otherwise destroying nature.
Today, kepone is banned under the Stockholm Convention on persistent organic pollutants.
Avoidance Costs Associated with Imperfect Information: The Case of Kepone.
29) In this case, the taxpayer pled nolo contendere to a 1,940-count indictment for waste and water pollution resulting from its manufacturing of Kepone.
DDT, aldrin, dieldrin, heptachlor, chlordane, kepone, nonylphenol, and alkylbenzene sulfonate) have shown 'hockey-stick' shaped loss curves involving an initial stage of relatively rapid loss followed by little or no loss (Alexander 1995).
14) In Hopewell, Virginia, production of the chemical Kepone by the Allied Chemical Company deteriorated employees' health and damaged the aquatic environment of the James River.
The then-recent kepone contamination of the James River, as well as discoveries about dangers posed by polychlorinated biphenyls (PCBs) and methyl chloride, prompted congressional concern that many existing chemicals posed significant health and environmental risks, and that no legal mechanism existed to impede the introduction of the next generation of equally dangerous chemicals.
1976), Kepone (Bookhout et al, 1980), and Mirex (Bookhout et al, 1972); components of drilling fluids (Bookhout et al, 1984a, b); polycylic aromatic hydrocarbons (Laughlin and Neff, 1979a, b, 1980, 1981; Laughlin et al.