Kepone


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Kepone

 [ke´pōn]
trademark for a polychlorinated ketone used as an insecticide; workers exposed to this nonbiodegradable compound have suffered neurologic symptoms, such as tremors and slurred speech.
A carcinogenic chlorinated polycyclic ketone insecticide and fungicide used in the US between 1966 and 1975. It gained notoriety from its improper handling and dumping into the James River, Virginia, which was subsequently closed to fishing. Chlordecone has a 30-year environmental half-life
Toxicity Tremors, nystagmus, memory loss, headaches, slurred speech, unsteadiness, incoordination, loss of weight, rash, hepatomegaly, decreased libido, sterility, chest pain, arthralgia, and the increased risk of cancer
References in periodicals archive ?
These chemicals include kepone, o,p-'-DDT and butylparaben (ESR1 agonist), and linuron and methoxychlor (AR antagonist) (Judson et al., 2015; Kleinstreuer et al., 2017).
Chlordecone (i.e., Kepone) contamination is a particular problem in the French Antilles because it was used extensively there until 1993 as an insecticide for banana weevil borer control (Boucher et al.
Guzelian, "Comparative toxicology of chlordecone (kepone) in humans and experimental animals," Annual Review of Pharmacology and Toxicology, vol.
Idiopathic rICP has been reported in several studies and also as a complication of a list of drugs, including chlordecone (kepone), ketoprofen or indomethacin in Bartter's syndrome, thyroid replacement therapy in hypothyroid children, tetracycline and its derivatives, amiodarone, hypervitaminosis A, lithium carbonate, nalidixic acid, sulfa antibiotics and risperidone.
On the issue of importing toxic waste from the US, a diplomat wrote: "EPA (the Environmental Protection Agency) has requested Department's assistance in confirming Allied Chemical Corporation contention that the UK Government has been informed of the trial incineration of 80 drums of Kepone scheduled to be performed by Rechem International Ltd, Pontypool, Wales.
The exhibition took place in the presence of the European Union Ambassador's Representative, Marcelo Mori, Swedish Ambassador to Lebanon, Nicholas kepone, and scores of concerned dignitaries.
Our area is no longer in a crisis (or perceived crisis) that causes it to take priority over other more pressing national problems such as terrorism and the financial crisis--as it once was when the Cuyahoga River caught fire, Kepone poisoned the James River, children in the inner city suffered retardation from lead in gasoline, and we believed that PCBs and other chlorinated organics were causing wide-spread sterility in the animal kingdom and otherwise destroying nature.
The production of the insecticide kepone, invented by Allied in 1966, had been licensed to Life Science Products Co., a Hopewell, Virginia-based company founded by two former Allied employees.
"Avoidance Costs Associated with Imperfect Information: The Case of Kepone." Land Economics, 57, 1981, 139-50.
(29) In this case, the taxpayer pled nolo contendere to a 1,940-count indictment for waste and water pollution resulting from its manufacturing of Kepone. The trial judge imposed a fine of $13,240,000 but indicated he wanted the money used to help those persons harmed by the pollution.
DDT, aldrin, dieldrin, heptachlor, chlordane, kepone, nonylphenol, and alkylbenzene sulfonate) have shown 'hockey-stick' shaped loss curves involving an initial stage of relatively rapid loss followed by little or no loss (Alexander 1995).