Kartagener's syndrome


Also found in: Dictionary, Thesaurus, Encyclopedia.
Related to Kartagener's syndrome: situs inversus, Kartagener's triad, Young's syndrome

Kartagener's syndrome

 [kahr-tag´ĕ-nerz]
a hereditary syndrome consisting of dextrocardia, bronchiectasis, and sinusitis.

Kartagener's syndrome

[kärtag′ənərz]
an inherited disorder characterized by bronchiectasis, chronic paranasal sinusitis, and transposed viscera, usually dextrocardia. Compare immotile cilia syndrome.

Kartagener's syndrome

The combination of congenital malfunction of the brush borders of the respiratory hair cells (cilia) with BRONCHIECTASIS, SINUSITIS and reversal (transposition) of the internal organs of the body. (Manes Kartagener, Swiss physician, b. 1897)

Kartagener's syndrome

a hereditary syndrome of humans consisting of dextrocardia, bronchiectasis and sinusitis. Cases of a similar disease are reported in dogs. The disease is primarily a defect in cilia motility. See also primary ciliary dyskinesia.
References in periodicals archive ?
Kartagener's Syndrome is a rare Autosomol recessive disorder presents as a triad of Sinusitis, Bronchiectasis and Situs inversus.
Absence of axonemal arms in nasal mucosa cilia in Kartagener's syndrome.
The chronic sinusitis associated with Kartagener's syndrome contributes to the development of bronchiectasis because the ciliated cells in the sinuses also function improperly, and cannot clear the mucus produced at these sites.
Primarily nasal origin of exhaled nitric oxide and absence in Kartagener's syndrome.
DISCUSSION: Kartagener's syndrome is characterised by the clinical trial of situs inversus, chronic sinusitis and/or nasal polyposis and bronchiectasis.
Such cases of PCD with situs inversus are known as Kartagener's syndrome.
A high index of suspicion is needed to detect Kartagener's syndrome (KS) early so that treatment options, if feasible can be considered for infertility in these patients.
The association of situs inversus with other syndromes and diseases such as Kartagener's syndrome, mucociliary dysfunction, airway anomalies, etc.
DISCUSSION: First described by Siewert and later by Swiss paediatrician Manes (1897-1975), Kartagener published his description of Kartagener's syndrome in 1933.