Patients eligible for randomization and treatment will be those (1) who have undergone debulking surgery, (2) for whom a cell line has been established, (3) who have undergone leukapheresis from which sufficient monocytes were obtained, (4) have an ECOG performance grade of 0 or 1 (Karnofsky
score of 70-100%), and (5) who have completed primary therapy.
I recently interviewed Ken Karnofsky
, senior strategist for signal processing applications at MathWorks, and got his thoughts on the evolution of wireless testing in recent years and the increasing part simulation has played along the way.
In terms of performance status, 11 out of 14 patients in this study who received IVC plus chemoradiation had Karnofsky
scores that remained stable, while two increased, one decreased, and there were two patients who withdrew from the study.
Researchers evaluated participant symptoms based on the Karnofsky
Performance Scale Index (KPSI), which classifies patients according to their functional impairment and fatigue.
Thus, the patients who are referred for palliative radiation therapy now may have more widespread disease that has become resistant to other therapies, as reflected in this study by the severity of pain scores (72% of the patients in this study had severe pain at study entry) and the Karnofsky
performance status scores (nearly 25% of the patients in this study had Karnofsky
performance status scores of 60 or lower, and more than 75% had Karnofsky
performance status scores of 80 or lower).
score" was included as part of the evaluation.
Outcome measures used were Glasgow coma score (GCS), Glasgow outcome score (GOS) and Karnofsky
performance score (KPS).
Clinical data including age, gender, comorbidities, histology, stage, Karnofsky
Performance Status (KPS), treatment history, and survival characteristics were collected for all the patients.
Very few companies have adequate resources or in-house expertise to understand and implement a 5G-compliant design, said Ken Karnofsky
, senior strategist signal processing applications, MathWorks.
These data sets also were compared with two common scales used to gauge physical status and overall health: the Eastern Cooperative Oncology Group Performance Status (ECOG) and Karnofsky
Performance Status (KPS) scales.