Kallmann's syndrome


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Kallmann's syndrome1

Etymology: Franz J. Kallmann, American psychiatrist, 1897-1965
a condition characterized by the absence of the sense of smell and longer-than-average limbs. It is caused by agenesis of the olfactory bulbs and secondary hypogonadism related to a decrease of luteinizing hormone-releasing hormone (interstitial cell-stimulating hormone).

Kallmann's syndrome2

[kahl′mahns]
a type of hypogonadotropic hypogonadism caused by failure of fetal gonadotropin-releasing hormone neurons to migrate to the thalamus, usually associated with anosmia or hyposmia. It is usually passed by autosomal-recessive inheritance and, in some cases, is X-linked.

Kallmann's syndrome

Absence of the sense of smell associated with a deficiency of the hormone from the HYPOTHALAMUS that prompts the PITUITARY GLAND to secrete a sex gland stimulating hormone (gonadotrophic releasing hormone). (Franz Josef Kallman, 1897–1965, German-born American geneticist and psychiatrist).