ADAM1baa10

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ADAM1baa10

A widely expressed member of the ADAMs family of proteins encoded by ADAM10 on chromosome 15q2|15q22.
Activity Controls proteolytic processing of Notch, mediates lateral inhibition in neurogenesis, cleaves pro-TNF-alpha, myelin basic protein, and type IV collagen. It is responsible for the proteolytic release of other cell-surface proteins, including heparin-binding epidermal growth-like factor, ephrin-A2 and for constitutive and regulated alpha-secretase cleavage of amyloid precursor protein (APP). ADAM 10 contributes to the normal cleavage of the cellular prion protein. Involved in the cleavage of the adhesion molecule L1 at the cell surface and in released membrane vesicles, suggesting a vesicle-based protease activity. ADAM 10 is inhibited by TIMP-1 and TIMP-3.
References in periodicals archive ?
According to details, the villages to benefit from Rahat Kot-Sakhara road include Matta, Sambat, Badarh, Kuza Drush khela, Bara Drush Khela, Asharai, Bagh Dheri, Rhata Kot, Shakara, Darmai, Kalakot, Nowkhara, Garai, Azad Banda, Kohistani Banda, Bar Lal Koh, Kuz Lal Koh, Bat Koh, Fazal Baig and the newly developed tourist area Gabeen Jabba.
According to details, the Villages to benefit from RahatKot to Sakhara road include Matta, Sambat, Badarh, Kuza Drush khela, Bara Drush Khela, Asharai, Bagh Dheri, Rhata Kot, Shakara, Darmai, Kalakot, Nowkhara, Garai, Azad Banda, Kohistani Banda, Bar Lal koh, Kuz Lal Koh, Bat koh, Fazal Baig and the newly developed tourist area Gabeen Jabba.
Islam 22-A (HUP); Kuz Shawar, 34Adeg 49.025' N and 72Adeg 18.
(Ingram), Zo (Ball) and Kuz (Kyle Kuzma) only played 23 games together this year.
"I think Josh Hart, Ingram, Kuz, Ball, I think they can all at some point in their careers be All-Stars and be leaders of their team.
During his years as head coach, Coach "Kuz" led his team to two state championship games, winning the title game in the 2004 season.
In a firearms-possession case, the defendant's Facebook post adopted the admission: It's Always Tucked, Kuz I'll B Damn If My Life Get Took!!
On that occasion, Pauline was part of the bronze medal winning team alongside Fiona and fellow Carnegie Harrier runner Lynne Kuz in 2009, and repeated the bronze achievement in 2011 with other top Scottish runners Debbie Martin-Consani and Sharon Law.
The Turkish-backed militants captured the villages of Hatat Homs, Qareh Kuz and Tal Sha'er to the West of al-Ra'i city on Sunday.
PESHAWAR -- At least one security official was martyred when three back to back Improvised Explosive Devices (IEDs) were blasted in Kuz Chamarkand, Tehsil Safi of Mohmand Agency on Saturday.
While 30 family packages were given in Union Council Komila, Kuz Jalkot, Dassu and Seo areas of Kohistan.