A gene on chromosome 17q21.2 that encodes a type-I keratin, an intermediate filament protein that heterodimerises with type-II keratins to form hair and nails.
A significant decline was seen with KRT1, KRT4, KRT13, and KRT77 while others were strongly upregulated (e.g., KRT35, KRT38, KRT72, KRT82, and KRT83) after redox stress.