diabetes mellitus, ketosis-prone

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diabetes mellitus, ketosis-prone

A form of diabetes (OMIM:612227), which presents as a classic type-1, type-2 or atypical presentation, most common in those of African ancestry. Insulin may be required, but patients can be weaned from it and have prolonged remission with metabolic control. Insulin resistance may be seen in obese patients.

Molecular pathology
Defects in PAX4, which encodes a transcription factor that plays critical roles in foetal development (e.g., of pancreatic islets), cause ketosis-prone diabetes.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
Adding donor chains to the KPD Pilot Program has been under consideration since 2008.
The aim of Hoppe's book is neither to produce just another narrative about the dependency of the German party on the "center" in Moscow nor to write a "history from below" or a study of local communist "milieus." (4) The author's focus is on the leadership, and he clearly situates himself on the side of Hermann Weber and his notion of "Stalinization." (5) However, this does not preclude a revision, as Hoppe states, of a one-dimensional view of the collaboration of KPD officials with the Comintern.
A detailed analysis of these spectra, combined with ultraviolet observations performed with the Hubble Space Telescope (HST), had led to the conclusion that KPD 0005+5106 has a temperature of 120,000 Kelvin, which made it the hottest member of its class.
By 1932, "the KPD and the Nazi movement recruited comparable numbers of workers" (131).
The KPD, the largest communist party outside Soviet Russia during the 1920s and early 1930s, was almost certainly one of the most fully Stalinised of the Comintern's 'national sections'.
The transplant center must be approved by UNOS to perform living donor kidney transplants; [the] candidate must be registered on the deceased donor wait list; the transplant center must have a designated contact for kidney paired donation; and the transplant center must agree to all rules associated with the KPD Pilot Program.
This episode played a critical role in the historical memory of the KPD for two reasons.
KPD Insurance has promoted Carlye Irwin to commercial lines account manager.
raw gas on fast track basis through a temporary facilities in order to combat the severe energy crisis in the country, this was declared as Phase-I of the KPD.
(12) Electoral results of the Kommunistische Partei Deutschlands (German Communist Party, KPD) in Penzberg fluctuated from a low point of 10.8 per cent in 1928 to a high point of 44.1 per cent at the Reichstag election of July 1932, while in the nearby mining town of PeiKenberg the Sozialdemokratische Partei Deutschlands (Social Democratic Party, SPD) held the upper hand, with fluctuating results there for the KPD between 2.8 per cent in 1928 to 19.1 per cent in November 1932.
"The idea is that UNOS has been thinking about the idea of a national paired donation system for quite a while, a number of years now, and we've gotten to the point where we're moving forward with a pilot program of the KPD Program.