KLF5


Also found in: Acronyms.

KLF5

A gene on chromosome 13q22.1 that encodes a protein of the Krüppel-like factor subfamily of zinc finger proteins; it localises to the nucleus, binds to GC box promoter elements and is thought to activate transcription of GC box genes.
References in periodicals archive ?
THSG reduces intima-media thickness in the aortic arch of SHRs, increases the vascular diastolic rate in response to acetylcholine, and reduces remodeling and fibrosis-related mRNA expression, such as that of genes ACTA2, CCL3, COL1A2, COL3A1, TIMP1 WISP2, IGFBP1, ECE1, KLF5, MYL1 BMP4, FN1, and the plasminogen activator inhibitor-1 (PAI-1).
Regulation of adipocyte differentiation by activation of serotonin (5-HT) receptors 5-HT2AR and 5-HT2CR and involvement of microRNA-448-mediated repression of KLF5.