KITLG

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KITLG

A gene on chromosome 12q22 that encodes KIT tyrosine kinase receptor ligand, which plays a key role in regulating cellular activities (such as: cell survival and proliferation; haematopoiesis; stem cell maintenance; gametogenesis; mast cell development; migration and function; and in melanogenesis) by activating multiple signalling pathways.

Molecular pathology
KITLG mutations cause familial progressive hyperpigmentation.
References in periodicals archive ?
Mining is permitted from the KL-1 & KL-2 kimberlite pipes each 10.
Development and trial mining has been restricted to the KL-1 and KL-2 Kimberlite pipes, each in excess of 10.
The KL-1 open pit is due to commence operations in November, 1996.