KITLG(redirected from KIT ligand)
KITLGA gene on chromosome 12q22 that encodes KIT tyrosine kinase receptor ligand, which plays a key role in regulating cellular activities (such as: cell survival and proliferation; haematopoiesis; stem cell maintenance; gametogenesis; mast cell development; migration and function; and in melanogenesis) by activating multiple signalling pathways.
KITLG mutations cause familial progressive hyperpigmentation.
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