The role of p21(waf1/cip1) and p27(Kip1
) in HDACi-mediated tumor cell death and cell cycle arrest in the E[micro]-myc model of B-cell lymphoma.
Campbell et al., "p27(Kip1
) is required to maintain proliferative quiescence in the adult cochlea and pituitary," Cell Cycle, vol.
Lee, "Constitutively active FOXO4 inhibits Akt activity, regulates p27 Kip1
stability, and suppresses HER2-mediated tumorigenicity," Oncogene, vol.
High level expression of p27(kip1
) and cyclin D1 in some human breast cancer cells: inverse correlation between the expression of p27(kip1
) and degree of malignancy in human breast and colorectal cancers.
Moreover, AMPK activation in immature oocytes apparently downregulates two MPF stimulators--target of rapamycin (TOR) and nitric oxide synthase (NOS) (Stricker, 2011, 2012)--while upregulating the MPF inhibitor p27 Kip1
(Stricker, 2011), collectively indicating that AMPK signaling serves to inhibit GVBD in nemerteans (Stricker et al., 2010a, b; Stricker, 2011).
) controls cytokinesis via the regulation of citron kinase activation.
Saint-Laurent et al., "sst2 somatostatin receptor mediates cell cycle arrest and induction of p27(Kip1
Liao, "3-hydroxy-3- methylglutaryl-CoA reductase inhibitors attenuate vascular smooth muscle proliferation by preventing Rho GTPase-induced down-regulation of p27(Kip1
)," The Journal of Biological Chemistry, vol.
) cell cycle 2006 progression 8 CDK6 Probably involved in Chilosi et al.
Constitutive MEK/MAPK activation leads to p27(Kip1
) deregulation and antioestrogen resistance in human breast cancer cells.
Regulation of the p27 (Kip1
) tumor suppressor by miR-221 and miR-222 promotes cancer cell proliferation.
1,25-Dihydroxyvitamin D3 induces differentiation of a retinoic acid-resistant acute promyelocytic leukemia cell line (UF-1) associated with expression of p21(WAF1/CIP1) and p27(KIP1