KIF21A

(redirected from KIF2)

KIF21A

A gene on chromosome 12q12 that encodes a member of the KIF4 subfamily of kinesin-like motor proteins that has an N-terminal motor domain, a coiled-coil stalk domain and a C-terminal WD-40 repeat domain. KIF21A may be involved in microtubule-dependent and in axonal transport.

Molecular pathology
KIF21A mutations cause congenital fibrosis of extraocular muscles-1.
References in periodicals archive ?
The activated eggs were stained with antibodies against tubulin, actin, NuMA, centrosomal proteins, and the kinesin-like proteins Kif2, KR[P.sub.110] and KR[P.sub.170], and stained cells were viewed on a laser-scanning confocal microscope.
Messenger RNA isoforms of two other kinesins, KHC and KIF2, were found to be enriched in myelin (data not shown).