KIF1C

KIF1C

A gene on chromosome 17p13.2 that encodes a motor protein required for the retrograde transport of Golgi vesicles to the endoplasmic reticulum.
References in periodicals archive ?
For example, KIF1C (kinesin family member 1C) and USP28 (ubiquitin specific peptidase 28) mutations, which are clonally expanded in metastasis, preexist at levels of [less than or equal to] 1% in primary breast tumors (8), and clinical resistance-causing KIT (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog) (gastrointestinal stromal tumor) and EGFR (lung adenocarcinoma) mutations can be present in tumors at levels <<1% (36, 37).
[5] Human genes: TET2, tet methylcytosine dioxygenase 2; KRAS, v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog; TP53, tumor suppressor protein 53; IDH1, isocitrate dehydrogenase subunit 1 ([NADP.sup.+]), soluble; EGFR, epidermal growth factor receptor; KIF1C, kinesin family member 1C; USP28, ubiquitin specific peptidase 28; KIT, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog.
Dietrich of the Howard Hughes Medical Institute and Harvard Medical School in Boston and his colleagues report that certain variations of a gene called Kif1C, which encodes a protein that ushers other proteins around inside cells, protect mice from the effects of the anthrax toxin.