KIF18A

KIF18A

A gene on chromosome 11p14.1 that encodes an ATP-dependent  member of the kinesin superfamily of microtubule-associated molecular motors.

Molecular pathology
ATIC mutation causes AICA-ribosiduria.
References in periodicals archive ?
E2 had a significant effect on the expression of genes associated with cell division (Top2a, Mki67, Ccnbl, Ccnb2; Figure 5A) and cytokinesis (Kifll, Kf2c, Kif18a; Figure 5B).
Although 8-PN weakly induced the expression of some of the E2 target genes (Kif11, Kif2c, Kif18a, Csn2), a significant counteracting effect of 3-MC on 8-PN-induced gene expression was observed for Csn2, Kif18a, and Kif11, in which the relative expression of the mRNA was significantly abrogated after co-treatment.