SENP2(redirected from KIAA1331)
SENP2A gene on chromosome 3q27.2 that encodes sentrin-specific peptidase 2, which has two key roles:
(1) Processing of full-length SUMO1, SUMO2 and SUMO3 to mature forms; and
(2) Deconjugating SUMO1, SUMO2 and SUMO3 from targeted proteins.
SENP2 may also downregulate CTNNB1 levels, thereby modulating the Wnt pathway.It is also a less preferred gene symbol for what is now designated as SUMO1, see there.
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